Table 3 |
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Inhibition of Platelet aggregation (PA) in human: |
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|
References |
Preparations |
Duration |
Effect |
|
|
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|
Bordia, 1978 [72] |
Garlic |
In-vitro |
Dose-dependent Platelet aggregation |
|
Vanderhock et al., 1980 [73] |
Garlic oil |
In vitro |
Inhibit PA |
|
Boullin, 1981 [80] |
Fresh garlic |
Single Dose |
Inhibit PA |
|
Ariga et al., 1981 [85] |
Methyl allyl trisulfide |
In vitro |
Inhibit PA |
|
Arora and Arora, 1981 [54] |
Ether extract of garlic |
Single Dose |
Increased coagulation time |
|
Bordia et al., 1982 [51] |
Ether extract of garlic |
3 weeks |
Inhibit PA |
|
Samson, 1982 [76] |
Essential garlic oil |
10 days |
No PA activity |
|
Apitz-Castro et al., 1983 [74] |
Garlic extract and 3 pure component |
In vitro |
Inhibit PA |
|
Block et al., 1984 [86] |
Ajoene |
In vitro |
Inhibit PA |
|
Srivastava, 1984 [61] |
Aqueous extract of garlic |
In vitro |
Inhibit PA |
|
Srivastava, 1986 [75] |
Aqueous extract of garlic |
In vitro |
Inhibit PA |
|
Harenberg et al., 1988 [77] |
Dried garlic powder |
4 weeks |
No PA activity |
|
Kiesewetter et al., 1991 [78] |
Garlic powder |
4 weeks |
Inhibit PA |
|
Kiesewetter et al., 1993 [87] |
Garlic powder |
4 weeks |
Inhibit PA |
|
Legnani et al., 1993 [56] |
Garlic powder |
Single Dose and 14 days |
Inhibit PA |
|
Morris et al., 1995 [88] |
Oil extract (equivalent to 15 gm of raw garlic) |
In-vitro and in-vivo (5 days) |
Inhibit PA in in-vitro No in-vivo PA activity |
|
Bordia et al., 1998 [57] |
Ethyl acetate extract of garlic |
In-vitro study |
Inhibit PA |
|
Sreiner and Lin, 1998 [79] |
Aged garlic extract |
10 months |
Inhibit PA |
|
Rahman and Billington, 2000 [28] |
Aged garlic extract |
13 weeks |
Inhibit PA |
|
Steiner and Li, 2001 [89] |
Aged garlic extract |
6 weeks |
Dose dependent inhibition of PA |
|
|
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Banerjee and Maulik Nutrition Journal 2002 1:4 doi:10.1186/1475-2891-1-4 |
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