Table 3

Inhibition of Platelet aggregation (PA) in human:

References

Preparations

Duration

Effect


Bordia, 1978 [72]

Garlic

In-vitro

Dose-dependent Platelet aggregation

Vanderhock et al., 1980 [73]

Garlic oil

In vitro

Inhibit PA

Boullin, 1981 [80]

Fresh garlic

Single Dose

Inhibit PA

Ariga et al., 1981 [85]

Methyl allyl trisulfide

In vitro

Inhibit PA

Arora and Arora, 1981 [54]

Ether extract of garlic

Single Dose

Increased coagulation time

Bordia et al., 1982 [51]

Ether extract of garlic

3 weeks

Inhibit PA

Samson, 1982 [76]

Essential garlic oil

10 days

No PA activity

Apitz-Castro et al., 1983 [74]

Garlic extract and 3 pure component

In vitro

Inhibit PA

Block et al., 1984 [86]

Ajoene

In vitro

Inhibit PA

Srivastava, 1984 [61]

Aqueous extract of garlic

In vitro

Inhibit PA

Srivastava, 1986 [75]

Aqueous extract of garlic

In vitro

Inhibit PA

Harenberg et al., 1988 [77]

Dried garlic powder

4 weeks

No PA activity

Kiesewetter et al., 1991 [78]

Garlic powder

4 weeks

Inhibit PA

Kiesewetter et al., 1993 [87]

Garlic powder

4 weeks

Inhibit PA

Legnani et al., 1993 [56]

Garlic powder

Single Dose and 14 days

Inhibit PA

Morris et al., 1995 [88]

Oil extract (equivalent to 15 gm of raw garlic)

In-vitro and in-vivo (5 days)

Inhibit PA in in-vitro No in-vivo PA activity

Bordia et al., 1998 [57]

Ethyl acetate extract of garlic

In-vitro study

Inhibit PA

Sreiner and Lin, 1998 [79]

Aged garlic extract

10 months

Inhibit PA

Rahman and Billington, 2000 [28]

Aged garlic extract

13 weeks

Inhibit PA

Steiner and Li, 2001 [89]

Aged garlic extract

6 weeks

Dose dependent inhibition of PA


Banerjee and Maulik Nutrition Journal 2002 1:4   doi:10.1186/1475-2891-1-4

Open Data