Table 2

Adjusted prevalence (with standard error) of and adjusted odds ratios (with 95% confidence intervals) for taking folic acid supplements among adults aged ≥ 18 years, by sex and by depression and anxiety status, BRFSS, 2006

Adjusted prevalence*

Adjusted odds ratio*

Taking supplements

No supplements

Taking supplements

(times/day)

< 1

1 to 4

< 1

1 to 4

% (SE)

% (SE)

% (SE)

AOR

95% CI

AOR

95% CI

Men (n = 18, 092)

Ever diagnosed depression

Yes (n = 2, 140)

7.6 (1.1)

45.1 (1.8)¶

47.3 (1.9)¶

1.42

1.00-2.00

1.44

1.21-1.71

No (n = 15, 952)

6.4 (0.4)

38.0 (0.6)

55.6 (0.6)

1.00

1.00

Ever diagnosed anxiety

Yes (n = 1, 508)

9.6 (1.8)†

43.6 (2.2)‡

46.8 (2.3)¶

1.83

1.18-2.84

1.39

1.13-1.70

No (n = 16, 584)

6.3 (0.4)

38.3 (0.6)

55.4 (0.6)

1.00

1.00

EDS

Yes (n = 1, 162)

10.6 (2.7)

37.5 (2.4)

52.0 (3.1)

1.79

0.96-3.34

1.02

0.80-1.30

No (n = 16, 930)

6.3 (0.4)

38.8 (0.6)

54.9 (0.6)

1.00

1.00

Women (n = 28, 027)

Ever diagnosed depression

Yes (n = 5, 879)

6.6 (0.6)

52.7 (1.1)‡

40.7 (1.0)‡

0.97

0.76-1.24

1.13

1.02-1.26

No (n = 22, 148)

7.2 (0.3)

49.8 (0.5)

43.0 (0.5)

1.00

1.00

Ever diagnosed anxiety

Yes (n = 4, 038)

7.0 (0.8)

51.8 (1.3)

41.3 (1.2)

1.02

0.78-1.33

1.08

0.96-1.22

No (n = 23, 989)

7.1 (0.3)

50.1 (0.5)

42.8 (0.5)

1.00

1.00

EDS

Yes (n = 2, 816)

7.5 (1.2)

49.2 (1.6)

43.2 (1.5)

1.05

0.73-1.51

0.96

0.83-1.10

No (n = 25, 211)

7.0 (0.3)

50.5 (0.5)

42.5 (0.5)

1.00

1.00

*Adjusted for age, race/ethnicity, education, body mass index, marital status, smoking, leisure-time exercise, and alcohol consumption. †P = 0.065, ‡P < 0.05, and ¶P < 0.001 for comparisons between adults with ever diagnosed depression or anxiety and those without. AOR = Adjusted odds ratio, BRFSS = Behavioral Risk Factor Surveillance System, CI = Confidence interval, EDS = Elevated depressive symptoms, SE = Standard error

Zhao et al. Nutrition Journal 2011 10:102   doi:10.1186/1475-2891-10-102