Table 2

Selection of significant peaks affected by diet and/or GSTM1 genotype¹

Peak (m/z)

EAT

2EAT

1 X Cruciferous¹

1 X Cruciferous²

2 X Cruciferous³

ALL

GSTM1-null

GSTM1+

ALL

GSTM1-null

GSTM1+

ALL

GSTM1-null

GSTM1+

4813

IR⁴

0.043

0.370

0.005

0.188

0.254

0.140

0.062

0.478

0.062

p-value

0.047*

0.619

0.031*

0.168

0.427

0.240

0.022*

0.664

0.005*

4905

IR

1.509

1.214

1.877

1.183

0.920

1.521

1.789

1.436

1.789

p-value

0.020*

0.384

0.022*

0.520

0.823

0.248

0.028*

0.326

0.033*

6500

IR

0.870

0.975

0.776

0.823

0.959

0.708

0.527

0.629

0.527

p-value

0.319

0.887

0.242

0.502

0.919

0.391

0.028*

0.248

0.048*

6700

IR

0.782

0.933

0.655

0.712

0.878

0.577

0.574

0.876

0.575

p-value

0.123

0.732

0.087

0.276

0.767

0.207

0.076

0.760

0.029*

9565

IR

0.744

1.229

0.451

0.745

0.966

0.575

0.569

0.629

0.569

p-value

0.044*

0.267

0.001*

0.064

0.879

0.012*

0.000*

0.038*

0.004*

9812

IR

1.218

1.131

1.312

1.167

0.870

1.565

1.494

1.458

1.494

p-value

0.036*

0.297

0.062

0.323

0.529

0.041*

0.011*

0.083

0.058*

¹1X cruciferous diet (basal diet supplemented with 436 g/day cruciferous vegetables) compared to EAT basal diet (fruit- and vegetable-free).

²1X cruciferous diet (basal diet supplemented with 7 g/kg body weight/day cruciferous vegetables) compared to 2EAT basal diet.

³2X cruciferous diet (basal diet supplemented with 14 g/kg body weight/day cruciferous vegetables) compared to 2EAT basal diet.

⁴IR denotes the cruciferous vegetable-to-basal diet peak intensity ratio in the unit of square root of estimand of between-subject variance.

* P < 0.05

Brauer et al. Nutrition Journal 2011 10:11   doi:10.1186/1475-2891-10-11