Table 3

Ferritin concentrations in Caco 2 cells exposed to samples of beans only (whole bean, 49 ppm Fe and 71 ppm Fe, "Low Fe" and "High Fe" beans, respectively) and bean-based diets digests; "Low Fe" bean diet (42 ppm Fe) and "High Fe" bean diet (54 ppm Fe).

Tested sample1

Ferritin (ng/mg of protein)


"Low Fe" bean only

7.82 ± 0.75d


"High Fe" bean only

30.6 ± 2.08a


"Low Fe" bean-based diet

11.2 ± 0.97c


"High Fe" bean-based diet

15.7 ± 1.05b


Baseline2

4.06 ± 0.37e


1Caco 2 bioassay procedures and preparation of the digested samples are described in the materials and methods sections.

2Cells were exposed to only MEM growth media without added food digests and Fe. Values are means ± SEM, n = 6. Means with no letters in common are significantly different, P < 0.05.

Tako et al. Nutrition Journal 2011 10:113   doi:10.1186/1475-2891-10-113

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