General design of the experiment. Gastric magnetic resonance (MRI) was performed at basal time (-10 min), after a beverage pre-load, at maximum satiety and at 120' minutes after the start of the meal. A blood sample was taken to assay ghrelin and cholecystokinin (CCK), measure gastrointestinal symptoms (GIS) (postprandial fullness, early satiety, nausea, bloating, epigastric pain, epigastric burning) and eating perceptions (EP) (hunger, desire to eat, prospective of food consumption); this was performed at the same times and also 60 mins following the start of the meal.
Cuomo et al. Nutrition Journal 2011 10:114 doi:10.1186/1475-2891-10-114