Table 2

Fasting concentrations and net incremental areas under the curve after 240 min (net iAUC 0-240 min)1 for inflammatory markers, insulin and triglycerides in 11 (8 women and 3 men) obese non-diabetic subjects in response to the four test-meals

Cod

Whey

Gluten

Casein


MCP-1

Fasting

22 ± 11

21 ± 7

23 ± 12

21 ± 11

iAUC 0-240 min (pg/ml·240 min)

- 826 ± 1255x

- 77 ± 1092y

-943 ± 925x

-469 ± 757xy

CCL5

Fasting

340 ± 238

490 ± 396

490 ± 321

409 ± 297

iAUC 0-240 min (pg/ml·240 min)

50 764 ± 58 218x

- 18 510 ± 81 999y

11 235 ± 55 558yz

44 488 ± 37 862xz

IL-1ra

Fasting

68 ± 18

79 ± 39

76 ± 34

66 ± 24

iAUC 0-240 min (pg/ml·240 min)

743 ± 2 871

-1 972 ± 4 005

-1 454 ± 5 068

2 173 ± 4 320

PDGF-bb1

Fasting

40 ± 41

161 ± 260

65 ± 78

110 ± 232

iAUC 0-240 min (pg/ml·240 min)

11 837 (6 285 - 20 952)

4 303 (2 102 - 6 995)

6 660 (4851 - 10 742)

8 604 (6348 - 10 435)

IFN-g

Fasting

25 ± 12

28 ± 25

30 ± 21

28 ± 24

iAUC 0-240 min (pg/ml·240 min)

865 ± 1 610

-1 300 ± 3 747

-791 ± 2 622

397 ± 2 614

Adiponectin

Fasting

1.5 ± 0.5

1.5 ± 0.6

1.5 ± 0.6

1.5 ± 0.5

iAUC 0-240 min (μg/ml·240 min)

-7.7 ± 48

-8.5 ± 49

6.3 ± 38

-6.9 ± 36

Eotaxin

Fasting

52 ± 12

53 ± 14

51 ± 14

49 ± 16

iAUC 0-240 min (pg/ml·240 min)

- 45 ± 819

601 ± 2237

- 64 ± 686

983 ± 1039

G-CSF

Fasting

11 ± 3

12 ± 6

11 ± 4

12 ± 7

iAUC 0-240 min (pg/ml·240 min)

23 ± 719

-420 ± 1 242

-114 ± 685

-194 ± 955

IP-10

Fasting

579 ± 166

558 ± 109

588 ± 226

542 ± 142

iAUC 0-240 min (pg/ml·240 min)

-2 343 ± 24 198

-10 371 ± 19 737

-3 403 ± 21 448

-5 159 ± 10 121

MIP-1b

Fasting

45 ± 16

46 ± 16

44 ± 14

43 ± 15

iAUC 0-240 min (pg/ml·240 min)

-908 ± 1 248

-331 ± 1 411

-302 ± 534

-219 ± 428

VEGF

Fasting

7 ± 3

10 ± 6

7 ± 3

8 ± 4

iAUC 0-240 min (pg/ml·240 min)

693 ± 921

270 ± 1 058

233 ± 448

317 ± 419

Insulin

Fasting

65 ± 28

63 ± 33

66 ± 31

62 ± 32

iAUC 0-240 min (pmol/l·240 min)

41 158 ± 11 003x

73 693 ± 28 022y

38 738 ± 10 691x

50 978 ± 21 477x

Triglycerides

Fasting

2.0 ± 1.0

1.8 ± 0.8

1.9 ± 0.7

1.8 ± 0.9

iAUC 0-240 min (mmol/l·240 min)

138 ± 108

122 ± 95

132 ± 95

127 ± 94


1All values are means ± SDs (normal distributions; mixed-effects model, Tukey's post hoc correction) or medians with interquartile ranges in parentheses (skewed distribution; mixed-effects model on normal distributed log-transformed data, Tukey's post hoc correction). Meals: energy-free soup plus 100 g butter and 45 g carbohydrate consumed with either 45 g cod, 45 g whey isolate, 45 g gluten or 45 g casein. MCP-1: monocyte chemotactic protein-1; CCL5: Chemokine ligand 5; IL-1ra: interleukin 1 receptor-antagonist; PDGF-bb1: platelet derived growth factor BB; IFN-g: interferon-gamma; G-CSF: granulocyte colony-stimulating factor; IP-10: interferon-gamma induced protein 10 kDa; MIP-1b: macrophage inflammatory protein 1b; VEGF: vascular endothelial growth factor. Values in a row with different superscript letters are significantly different, P < 0.05.

Holmer-Jensen et al. Nutrition Journal 2011 10:115   doi:10.1186/1475-2891-10-115

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