Table 2 |
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|
Fasting concentrations and net incremental areas under the curve after 240 min (net iAUC 0-240 min)1 for inflammatory markers, insulin and triglycerides in 11 (8 women and 3 men) obese non-diabetic subjects in response to the four test-meals |
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|
Cod |
Whey |
Gluten |
Casein |
|
|
|
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|
MCP-1 |
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|
Fasting |
22 ± 11 |
21 ± 7 |
23 ± 12 |
21 ± 11 |
|
iAUC 0-240 min (pg/ml·240 min) |
- 826 ± 1255x |
- 77 ± 1092y |
-943 ± 925x |
-469 ± 757xy |
|
CCL5 |
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|
Fasting |
340 ± 238 |
490 ± 396 |
490 ± 321 |
409 ± 297 |
|
iAUC 0-240 min (pg/ml·240 min) |
50 764 ± 58 218x |
- 18 510 ± 81 999y |
11 235 ± 55 558yz |
44 488 ± 37 862xz |
|
IL-1ra |
||||
|
Fasting |
68 ± 18 |
79 ± 39 |
76 ± 34 |
66 ± 24 |
|
iAUC 0-240 min (pg/ml·240 min) |
743 ± 2 871 |
-1 972 ± 4 005 |
-1 454 ± 5 068 |
2 173 ± 4 320 |
|
PDGF-bb1 |
||||
|
Fasting |
40 ± 41 |
161 ± 260 |
65 ± 78 |
110 ± 232 |
|
iAUC 0-240 min (pg/ml·240 min) |
11 837 (6 285 - 20 952) |
4 303 (2 102 - 6 995) |
6 660 (4851 - 10 742) |
8 604 (6348 - 10 435) |
|
IFN-g |
||||
|
Fasting |
25 ± 12 |
28 ± 25 |
30 ± 21 |
28 ± 24 |
|
iAUC 0-240 min (pg/ml·240 min) |
865 ± 1 610 |
-1 300 ± 3 747 |
-791 ± 2 622 |
397 ± 2 614 |
|
Adiponectin |
||||
|
Fasting |
1.5 ± 0.5 |
1.5 ± 0.6 |
1.5 ± 0.6 |
1.5 ± 0.5 |
|
iAUC 0-240 min (μg/ml·240 min) |
-7.7 ± 48 |
-8.5 ± 49 |
6.3 ± 38 |
-6.9 ± 36 |
|
Eotaxin |
||||
|
Fasting |
52 ± 12 |
53 ± 14 |
51 ± 14 |
49 ± 16 |
|
iAUC 0-240 min (pg/ml·240 min) |
- 45 ± 819 |
601 ± 2237 |
- 64 ± 686 |
983 ± 1039 |
|
G-CSF |
||||
|
Fasting |
11 ± 3 |
12 ± 6 |
11 ± 4 |
12 ± 7 |
|
iAUC 0-240 min (pg/ml·240 min) |
23 ± 719 |
-420 ± 1 242 |
-114 ± 685 |
-194 ± 955 |
|
IP-10 |
||||
|
Fasting |
579 ± 166 |
558 ± 109 |
588 ± 226 |
542 ± 142 |
|
iAUC 0-240 min (pg/ml·240 min) |
-2 343 ± 24 198 |
-10 371 ± 19 737 |
-3 403 ± 21 448 |
-5 159 ± 10 121 |
|
MIP-1b |
||||
|
Fasting |
45 ± 16 |
46 ± 16 |
44 ± 14 |
43 ± 15 |
|
iAUC 0-240 min (pg/ml·240 min) |
-908 ± 1 248 |
-331 ± 1 411 |
-302 ± 534 |
-219 ± 428 |
|
VEGF |
||||
|
Fasting |
7 ± 3 |
10 ± 6 |
7 ± 3 |
8 ± 4 |
|
iAUC 0-240 min (pg/ml·240 min) |
693 ± 921 |
270 ± 1 058 |
233 ± 448 |
317 ± 419 |
|
Insulin |
||||
|
Fasting |
65 ± 28 |
63 ± 33 |
66 ± 31 |
62 ± 32 |
|
iAUC 0-240 min (pmol/l·240 min) |
41 158 ± 11 003x |
73 693 ± 28 022y |
38 738 ± 10 691x |
50 978 ± 21 477x |
|
Triglycerides |
||||
|
Fasting |
2.0 ± 1.0 |
1.8 ± 0.8 |
1.9 ± 0.7 |
1.8 ± 0.9 |
|
iAUC 0-240 min (mmol/l·240 min) |
138 ± 108 |
122 ± 95 |
132 ± 95 |
127 ± 94 |
|
|
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|
1All values are means ± SDs (normal distributions; mixed-effects model, Tukey's post hoc correction) or medians with interquartile ranges in parentheses (skewed distribution; mixed-effects model on normal distributed log-transformed data, Tukey's post hoc correction). Meals: energy-free soup plus 100 g butter and 45 g carbohydrate consumed with either 45 g cod, 45 g whey isolate, 45 g gluten or 45 g casein. MCP-1: monocyte chemotactic protein-1; CCL5: Chemokine ligand 5; IL-1ra: interleukin 1 receptor-antagonist; PDGF-bb1: platelet derived growth factor BB; IFN-g: interferon-gamma; G-CSF: granulocyte colony-stimulating factor; IP-10: interferon-gamma induced protein 10 kDa; MIP-1b: macrophage inflammatory protein 1b; VEGF: vascular endothelial growth factor. Values in a row with different superscript letters are significantly different, P < 0.05. |
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|
Holmer-Jensen et al. Nutrition Journal 2011 10:115 doi:10.1186/1475-2891-10-115 |
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