Table 1

Summary of measures assessed over the study duration.

Outcome measures and covariates

Time points (months)


~ -3

0

6

12

18


MMSE

x

x

x


Cognitive measures

x

x

x

x


Physical activity, functional capacity, and well-being measures

x

x

x

x


Height

x


Blood pressure, weight

x

x

x

x


Erythrocyte membrane n-3 and n-6 fatty acid status

x

x

x

x


Serum folate and Vitamin B12, and plasma carotenoid levels

x

x


Lipids, glucose, glycated haemoglobin, homocysteine

x

x


Medications, supplement use, adverse events and health changes

x

x

x

x


ApoE genotype

x


Inflammation (CRP), oxidative stress (MDA), and telomere length

x

x


Dietary data - general FFQ

x

x


Dietary data - n-3 consumption FFQ

x

x

x

x


Dietary data - historical seafood consumption FFQ

x


Abbreviations: MMSE = Mini-mental state examination; n-3 = omega-3; n-6 = omega-6; FFQ = food frequency questionnaire; ApoE = Apolipoprotein E.

Danthiir et al. Nutrition Journal 2011 10:117   doi:10.1186/1475-2891-10-117

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