Table 3

Effect of multivitamin supplementation on laboratory parameters

Outcome

Time Point (n)a

Placebo

Multivitamins

Hodges-Lehmann

p-valuec

Median (IQR)b

Median (IQR)b

95% CI

(Multivitamin-Placebo)


Hemoglobin, g/dL

Baseline (251)

8.70 (7.70, 9.80)

8.40 (7.40, 9.50)

(-0.20, 0.60)

0.28

Final (225)

9.40 (8.45, 10.25)

9.60 (8.70, 10.60)

(0.00, 0.70)

0.05

Change (223)

0.40 (-0.30, 1.40)

1.00 (0.30, 2.30)

(0.30, 1.00)

0.0001

Albumin, g/L

Baseline (253)

33.95 (29.90, 38.90)

34.00 (29.80, 39.10)

(-1.70, 1.70)

0.92

Final (232)

40.20 (36.30, 42.90)

38.90 (33.80, 42.50)

(-2.70, 0.10)

0.08

Change (231)

4.55 (0.10, 9.60)

3.40 (0.60, 7.00)

(-2.60, 0.60)

0.21

CD4, cells/μL

Baseline (242)

1592.50 (1099.00, 2254.00)

1351.50 (803.00, 2208.50)

(-410.00, 45.00)

0.11

Final (212)

1507.50 (1038.50, 2011.50)

1410.50 (782.50, 1904.50)

(-373.00, 71.00)

0.19

Change (207)

-63.00 (-506.00, 240.00)

-59.50 (-448.00, 261.00)

(-204.00, 140.00)

0.73

CD8, cells/μL

Baseline (242)

1233.00 (902.00, 2230.00)

1492.00 (988.00, 2624.00)

(-16.00, 450.00)

0.06

Final (212)

1328.00 (921.50, 2208.50)

1506.50 (1039.00, 2742.00)

(-98.00, 389.00)

0.24

Change (207)

-130.00 (-489.00, 394.00)

-77.50 (-735.00, 432.00)

(-322.00, 193.00)

0.68

CD3, cells/μL

Baseline (242)

3317.50 (2423.00, 4616.00)

3593.50 (2430.00, 5211.50)

(-311.00, 590.00)

0.53

Final (212)

3176.00 (2269.00, 4676.50)

3540.50 (2871.00, 4614.50)

(-154.00, 681.00)

0.21

Change (207)

-223.00 (-1149.00, 724.00)

-324.00 (-1179.00, 889.00)

(-519.00, 466.00)

0.89


a Final at 8 weeks follow-up; Change between the final and the baseline measurement

b IQR: Interquartile Range

c p-value based on Wilcoxon 2-group comparison

Mehta et al. Nutrition Journal 2011 10:120   doi:10.1186/1475-2891-10-120

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