Table 4

Odds ratios (ORs) and 95% confidence intervals (CI) for joint effect of energy-adjusted vitamin E and folate intake on esophageal squamous cell carcinoma risk in a case-control study in Iran1,2

Folate


Model 13

Model 24



Low

Medium

High

Low

Medium

High


Vitamin E

Low Number

1.00 (32)

0.51 (0.19-0.72) (15)

0.44 (0.13-0.90) (4)

1.00

0.48 (0.11-0.75)

0.48 (0.11-0.75)

Medium Number

0.63 (0.09-0.86) (14)

0.08 (0.01-0.47) (23)

0.07 (0.01-0.69) (11)

0.52 (0.09-0.81)

0.05 (0.01-0.39)

0.05 (0.02-0.41)

High Number

0.22 (0.01-0.79) (2)

0.05 (0.00-0.76) (9)

0.01 (0.00-0.79) (33)

0.19 (0.05-0.66)

0.04 (0.01-0.42)

0.02 (0.00-0.87)


1Nutrient intakes are adjusted for energy intake using the residual method [62]

2P for interaction = 0.03

3Base model; adjusted for age (years) and sex (male/female)

4Fully-adjusted model; adjusted for age (years), sex (male/female), gastroesophageal reflux disease symptoms (yes/no), body mass index (≤24.9, >24.9 kg/m2), smoking status (never/former/current), smoking intensity and duration (<20, ≥20 pack-years), physical activity (MET) (light/heavy), and education level (illiterate, literate)

Jessri et al. Nutrition Journal 2011 10:137   doi:10.1186/1475-2891-10-137

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