Table 2 |
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Changes of metabolic parameters and liver functions in HCC subjects with different BMI, GA, FFA |
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|
BMI(median) |
P |
GA(median) |
P |
FFA(median)or (X±SD) |
P |
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|
|
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|
<24 kg/cm2 |
≥24 kg/cm2 |
≤16% |
>16% |
≤0.6 |
>0.6 |
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|
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|
BMI (kg/m2) |
22.6 (20.70~25.19) |
23.24 (21.15~24.67) |
0.86 |
22.45 (21.68~24.73) |
24.67 (20.62~26.08) |
0.45 |
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|
GA |
15(14~16) |
16(13~16) |
0.08 |
15.5(14~16) |
14.5(14~16) |
0.18 |
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|
GLU (mmol/L) |
4.96(4.48~5,23) |
5.2(4.68~5.39) |
0.03 |
4.86 (4.54~5.1) |
6.43(5.06~6.59) |
0.00 |
5.03(4.59~5.38) |
5.17(4.67~5.39) |
0.64 |
|
INS (μU/L) |
7.46(3.79~7.47) |
7.77(5.15~10.18) |
0.00 |
7.46(3.97~8.93) |
9.06(3.92~10.03) |
0.81 |
7.32 (4.15~9.16) |
8.32(4.29~10.38) |
0.29 |
|
C-peptide (nmol/L) |
1.18(0.84~1.39) |
1.18(1.13~1.95) |
0.00 |
1.16(0.91~1.55) |
1.26(0.96~1.53) |
0.92 |
1.18(1.0~1.56) |
1.24 (1.16~2.0) |
0.04 |
|
IR |
1.53(0.8~1.62) |
1.9(1.11.~2.54) |
0.00 |
1.43(0.87~2.03) |
3.16(0.90~2.44) |
0.07 |
1.5(0.90~2.06) |
2.59 (1.12~2.41) |
0.11 |
|
QUICKI |
0.36(0.35~0.39) |
0.35(0.33~0.37) |
0.00 |
0.36(0.34~0.39) |
0.32(0.33~0.39) |
0.07 |
0.36(0.34~0.38) |
0.33(0.33~0.37) |
0.11 |
|
FFA (mmol/L) |
0.39(0~0.54) |
0.61(0~0.58) |
0.03 |
0.46(0~0.56) |
0.5(0.1~0.57) |
0.32 |
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|
TC(mmol/L) |
3.60(3.31~4.42) |
4.44(3.55~4.71) |
0.04 |
3.84(0.35~0.46) |
4.26(3.42~4.49) |
0.59 |
3.83(3.4~4.48) |
4.32(3.63~4.67) |
0.36 |
|
TG(mmol/L) |
0.79(0.61~1.02) |
1.20(0.83~1.31) |
0.00 |
1.17(0.68~1.17) |
0.79(0.64~1.05) |
0.38 |
1.05(0.73~1.17) |
1.12(0.8~1.21) |
0.63 |
|
LDL(mmol/L) |
2.24(1.92~2.64) |
2.77(2.2~3.04) |
0.00 |
2.42(1.93~2.86) |
2.61(1.95~2.77) |
0.68 |
2.39(1.96~2.87) |
2.4(2.02~2.89) |
0.70 |
|
HDL(mmol/L) |
1.31(1.14~1.59) |
1.38(1.09~1.48) |
0.04 |
1.32(1.08~1.48) |
1.35(1.22~1.63) |
0.03 |
1.33(1.07~1.49) |
1.35(1.19~1.53) |
0.46 |
|
MDA(nmol/mL) |
10.75(7.48~15.8) |
10.88(6.22~14.05) |
0.34 |
10.63(6.97~15.38) |
12(6.38~14.73) |
0.98 |
11.24 ± 6.74 |
15.03 ± 12.33 |
0.03 |
|
TAOC(U/ml) |
12.03(10.64~17.13) |
15.36(10.36~18.19) |
0.21 |
12.46(10.47~17.04) |
16.84(11.63~18.53) |
0.05 |
11.96(9.22~17.51) |
14.4(10.85~17.82) |
0.20 |
|
ALB(g/L) |
41.6(38.45~43.63) |
39.6(38.6~43.2) |
0.84 |
41.6(39.04~43.7) |
39.2(37.2~42) |
0.02 |
41.8(38.74~43.49) |
39.95(37.13~42.08) |
0.10 |
|
ALT(U/L) |
30.2(26.53~55.93) |
44.5(26.5~53.4) |
0.89 |
30.2(25.95~53.75) |
49.9(32.15~56.7) |
0.27 |
38.85(25.65~56.65) |
31.95(29.18~56.35) |
0.72 |
|
AST(U/L) |
34.6(29.68~55.68) |
34.9(25.4~58.2) |
0.10 |
33.5(26.43~53.53) |
44.6(29.65~64.25) |
0.12 |
34.85(27.2~51.5) |
31.62(30.03~66.75) |
0.14 |
|
ALP(U/L) |
97(76~122) |
79(63~105) |
0.06 |
84(67~110.25) |
112(82~144) |
0.01 |
88.5(70.5~113) |
89(74.5~159.25) |
0.07 |
|
GGT(U/L) |
77(40~171) |
55(36~123) |
0.30 |
65(36~135) |
77(42~109) |
0.60 |
62(35.5~99) |
144(81~215.5) |
0.00 |
|
|
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|
Data were presented as median and range. Differences were regarded as significant at 0.05 in a Mann-Whitney U test. *p value < 0.05 was considered statistically significant. |
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Zhao et al. Nutrition Journal 2011 10:49 doi:10.1186/1475-2891-10-49 |
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