Table 3 |
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|
Factors associated with low vitamin B12 and folate among HIV infected children in Uganda |
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|
Baseline characteristics |
Number N |
Low vitamin B12 statusa n (%) |
Un adjusted OR (95% CI) |
Adjusted OR (95%CI) |
|
|
||||
|
Vitamin B12 status |
||||
|
Age < 24 months |
70 |
19 (27.1) |
0.9 (0.6 - 1.5) |
|
|
Age ≥ 24 months |
144 |
41 (28.5) |
||
|
Male |
100 |
33 (33.0) |
1.4 (0.9 - 2.1) |
1.6 (0.8 - 3.1) |
|
Female |
114 |
27 (23.7) |
||
|
Weight for height z score < -2 |
28 |
7 (25.0) |
0.9 (0.4 - 1.7) |
|
|
Weight for height z score ≥ -2 |
182 |
52 (28.6) |
||
|
Haemoglobin < 11 g/dl |
127 |
37 (29.1) |
1.1 (0.7 - 1.7) |
|
|
Haemoglobin ≥ 11 g/dl |
87 |
23 (26.4) |
||
|
CD4+ < 25% |
114 |
33 (28.9) |
1.1 (0.6 - 2.1) |
|
|
CD4+ ≥ 25% |
85 |
23 (27.1) |
||
|
On HAART |
44 |
15 (34.1) |
1.3 (0.8 - 2.1) |
|
|
HAART naïve |
170 |
45 (26.5) |
||
|
Routine CTX prophylaxis |
193 |
56 (29.0) |
1.5 (0.6 - 3.8) |
|
|
No routine CTX prophylaxis |
21 |
4 (19.0) |
||
|
Previous routine multivitamins |
144 |
40 (27.8) |
1.0 (0.6 - 1.5) |
|
|
No routine multivitamins |
70 |
20 (28.6) |
||
|
Folate status |
Low folate |
|||
|
Age < 24 months |
70 |
27 (38.6) |
1.6 (1.1 - 2.4) |
2.2 (1.1 - 4.5) |
|
Age ≥ 24 months |
144 |
35 (24.3) |
||
|
Male |
100 |
36 (36.0) |
1.6 (1.0 - 2.4) |
2.1 (1.1 - 4.0) |
|
Female |
114 |
26 (22.8) |
||
|
Weight for height z score < -2 |
28 |
7 (25.0) |
0.8 (0.4 - 1.7) |
|
|
Weight for height z score ≥ -2 |
182 |
54 (29.7) |
||
|
Haemoglobin < 11 g/dl |
127 |
45 (35.4) |
1.8 (1.1 - 2.9) |
1.9 (0.9 - 4.6) |
|
Haemoglobin ≥ 11 g/dl |
87 |
17 (19.5) |
||
|
CD4+ < 25% |
114 |
36 (31.6) |
1.2 (0.7 - 1.9) |
|
|
CD4+ ≥ 25% |
85 |
22 (25.9) |
||
|
On HAART |
44 |
10 (22.7) |
0.7 (0.4 - 1.3) |
|
|
HAART naïve |
170 |
52 (30.6) |
||
|
Routine CTX prophylaxis |
193 |
58 (30.1) |
1.6 (0.6 - 3.9) |
|
|
No routine CTX prophylaxis |
21 |
4 (19.0) |
||
|
Previous routine multivitamins |
144 |
44 (30.6) |
1.2 (0.7 - 1.9) |
|
|
No routine multivitamins |
70 |
18 (25.7) |
||
|
|
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|
aLow vitamin B12 < 221 pmol/L, Low folate < 13.4 nmol/L |
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|
Ndeezi et al. Nutrition Journal 2011 10:56 doi:10.1186/1475-2891-10-56 |
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