Table 3

Factors associated with low vitamin B12 and folate among HIV infected children in Uganda

Baseline characteristics

Number N

Low vitamin B12 statusa n (%)

Un adjusted OR (95% CI)

Adjusted OR (95%CI)


Vitamin B12 status

Age < 24 months

70

19 (27.1)

0.9 (0.6 - 1.5)

Age ≥ 24 months

144

41 (28.5)

Male

100

33 (33.0)

1.4 (0.9 - 2.1)

1.6 (0.8 - 3.1)

Female

114

27 (23.7)

Weight for height z score < -2

28

7 (25.0)

0.9 (0.4 - 1.7)

Weight for height z score ≥ -2

182

52 (28.6)

Haemoglobin < 11 g/dl

127

37 (29.1)

1.1 (0.7 - 1.7)

Haemoglobin ≥ 11 g/dl

87

23 (26.4)

CD4+ < 25%

114

33 (28.9)

1.1 (0.6 - 2.1)

CD4+ ≥ 25%

85

23 (27.1)

On HAART

44

15 (34.1)

1.3 (0.8 - 2.1)

HAART naïve

170

45 (26.5)

Routine CTX prophylaxis

193

56 (29.0)

1.5 (0.6 - 3.8)

No routine CTX prophylaxis

21

4 (19.0)

Previous routine multivitamins

144

40 (27.8)

1.0 (0.6 - 1.5)

No routine multivitamins

70

20 (28.6)

Folate status

Low folate

Age < 24 months

70

27 (38.6)

1.6 (1.1 - 2.4)

2.2 (1.1 - 4.5)

Age ≥ 24 months

144

35 (24.3)

Male

100

36 (36.0)

1.6 (1.0 - 2.4)

2.1 (1.1 - 4.0)

Female

114

26 (22.8)

Weight for height z score < -2

28

7 (25.0)

0.8 (0.4 - 1.7)

Weight for height z score ≥ -2

182

54 (29.7)

Haemoglobin < 11 g/dl

127

45 (35.4)

1.8 (1.1 - 2.9)

1.9 (0.9 - 4.6)

Haemoglobin ≥ 11 g/dl

87

17 (19.5)

CD4+ < 25%

114

36 (31.6)

1.2 (0.7 - 1.9)

CD4+ ≥ 25%

85

22 (25.9)

On HAART

44

10 (22.7)

0.7 (0.4 - 1.3)

HAART naïve

170

52 (30.6)

Routine CTX prophylaxis

193

58 (30.1)

1.6 (0.6 - 3.9)

No routine CTX prophylaxis

21

4 (19.0)

Previous routine multivitamins

144

44 (30.6)

1.2 (0.7 - 1.9)

No routine multivitamins

70

18 (25.7)


aLow vitamin B12 < 221 pmol/L,

Low folate < 13.4 nmol/L

Ndeezi et al. Nutrition Journal 2011 10:56   doi:10.1186/1475-2891-10-56

Open Data