Table 8

Multi regression analysis in which MTHFR polymorphism, Homocysteine level, HCV genotype and lipid profile as a independent variables for fibrosis1+2

Variables

OR (CI 95%)

p*

OR adjusted

p

OR adjusted

p

Gender: F/M

0.9 (0.5-1.7)

0.87

1.1 (0.5-2.4)

0.85

1.1 (0.5-2.4)

0.82

HOM- ≥ 2.5

0.8 (0.4-1.8)

0.55

0.8 (0.4-1.8)

0.63

0.8 (0.4-1.8)

0.57

LDL cholesterol ≥ 130

2.1 (0.4-10)

0.51

2.2 (0.4-11.1)

0.34

-(**)

-

HDL cholesterol ≤ 40

1.0 (0.4-2.3)

1.00

1.3 (0.6-3.2)

0.51

1.3 (0.5-3.2)

0.53

Tot-l Cholesterol ≥ 200

1.7 (0.3-8.3)

0.73

-(**)

-

1.8 (0.3-9.2)

0.49

Triglyceride ≥ 150

1.4 (0.4-5.3)

0.76

1.3 (0.3-5.0)

0.70

1.3 (0.3-5.1)

0.72

TT+CT (MTHFR)

0.9 (0.5-1.7)

0.75

1.4 (0.7-3.1)

0.39

1.4 (0.6-3.1)

0.39

Homocysteine ≥ 9

0.6 (0.3-1.3)

0.17

0.7(0.3-1.5)

0.34

0.7 (0.3-1.5)

0.35

*Fisher Test ** Collinearity

References values:

Triglyceride < 150 mg/dL, Total Cholesterol < 200 mg/dL, LDL-c < 130 mg/dL, HDL-c > 40 mg/dL, HOMA: < 2.5, Homocysteine < 9.0 μmol/L.

CI: confidence interval

Siqueira et al. Nutrition Journal 2011 10:86   doi:10.1186/1475-2891-10-86