Table 2 |
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|
Distribution of cases and controls according to races, genotypes and allelic frequencies of the MTHFR gene |
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|
MTHFR C > T |
Cases (n = 200) |
Controls (n = 167) |
* P-value |
**OR (95% CI) |
|
|
||||
|
CC, n (%) |
159 (79.50) |
125 (74.85) |
p = 0.392 |
1.11 (0.47-2.60) |
|
Chinese, n (%) |
30 (18.87) |
21 (16.80) |
χ2 = 0.733 |
|
|
Indian, n (%) |
57 (35.85) |
49 (39.20) |
||
|
Malay, n (%) |
72 (45.28) |
55 (44.00) |
||
|
CT, n (%) |
41 (20.50) |
40 (23.95) |
||
|
Chinese, n (%) |
9 (21.95) |
11 (27.50) |
||
|
Indian, n (%) |
10 (24.39) |
22 (55.00) |
||
|
Malay, n (%) |
22 (53.66) |
7 (17.50) |
||
|
TT, n (%) |
0 (0.00) |
2 (1.20) |
||
|
Chinese, n (%) |
0 (0.00) |
1 (50.00) |
||
|
Indian, n (%) |
0 (0.00) |
1 (50.00) |
||
|
Malay, n (%) |
0 (0.00) |
0 (0.00) |
||
|
ALLELE |
||||
|
C (%) |
359 (89.75) |
290 (86.83) |
p = 0.218 |
|
|
T (%) |
41 (10.25) |
44 (13.17) |
χ2 = 1.520 |
|
|
|
||||
|
* P-values obtained for the χ2 test for the genotypes distribution or allelic frequencies between cases and controls. ** OR is the risk of genotype CT in cases compared to controls |
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|
Liew et al. Nutrition Journal 2012 11:1 doi:10.1186/1475-2891-11-1 |
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