Table 2

Distribution of cases and controls according to races, genotypes and allelic frequencies of the MTHFR gene

MTHFR C > T

Cases

(n = 200)

Controls

(n = 167)

* P-value

**OR (95% CI)


CC, n (%)

159 (79.50)

125 (74.85)

p = 0.392

1.11 (0.47-2.60)

Chinese, n (%)

30 (18.87)

21 (16.80)

χ2 = 0.733

Indian, n (%)

57 (35.85)

49 (39.20)

Malay, n (%)

72 (45.28)

55 (44.00)

CT, n (%)

41 (20.50)

40 (23.95)

Chinese, n (%)

9 (21.95)

11 (27.50)

Indian, n (%)

10 (24.39)

22 (55.00)

Malay, n (%)

22 (53.66)

7 (17.50)

TT, n (%)

0 (0.00)

2 (1.20)

Chinese, n (%)

0 (0.00)

1 (50.00)

Indian, n (%)

0 (0.00)

1 (50.00)

Malay, n (%)

0 (0.00)

0 (0.00)

ALLELE

C (%)

359 (89.75)

290 (86.83)

p = 0.218

T (%)

41 (10.25)

44 (13.17)

χ2 = 1.520


* P-values obtained for the χ2 test for the genotypes distribution or allelic frequencies between cases and controls.

** OR is the risk of genotype CT in cases compared to controls

Liew et al. Nutrition Journal 2012 11:1   doi:10.1186/1475-2891-11-1

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