Table 3 |
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|
Associations (adjusted OR, 95%CI) of total energy, macronutrients, and alcohol intakes with CRC risk, CRC case-control study in NL and ON |
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|
Intakes of total energy, macronutrients, and alcohol |
Quintiles of intakes |
p-trendb |
||
|
|
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|
Q1e |
Q3e |
Q5e |
||
|
|
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|
Total energy |
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|
No. of cases/controls |
313/537 |
343/505 |
404/443 |
|
|
Median intake (kcal/day) |
1348.5 |
2109.3 |
3308.9 |
|
|
ORa (95% CI) |
1.00 |
1.19(0.92,1.53) |
1.56*(1.21,2.01) |
0.02 |
|
Protein |
||||
|
No. of cases/controls |
372/479 |
334/513 |
335/512 |
|
|
Median intake (g/day) |
68.4 |
85.6 |
106.7 |
|
|
ORa (95% CI) |
1.00 |
0.88(0.70,1.11) |
0.85*(0.69,1.00) |
0.06 |
|
Carbohydrate |
||||
|
No. of cases/controls |
392/458 |
332/516 |
334/513 |
|
|
Median intake (g/day) |
229.1 |
282.6 |
341.5 |
|
|
ORa (95% CI) |
1.00 |
0.84(0.67,1.02) |
0.81*(0.63,1.00) |
0.05 |
|
Total Fat |
||||
|
No. of cases/controls |
344/506 |
362/487 |
372/475 |
|
|
Median intake (g/day) |
60.1 |
80.5 |
102.8 |
|
|
ORa (95% CI) |
1.00 |
1.18(0.94,1.50) |
0.96(0.75,1.22) |
0.71 |
|
Total dietary fibre |
||||
|
No. of cases/controls |
388/462 |
355/493 |
308/539 |
|
|
Median intake (g/day) |
15.1 |
23.7 |
35.2 |
|
|
ORa (95% CI) |
1.00 |
0.97(0.77,1.23) |
0.84*(0.67,0.99) |
0.04 |
|
Saturated Fatty Acids |
||||
|
No. of cases/controls |
346/504 |
331/517 |
378/469 |
|
|
Median intake (g/day) |
19.0 |
26.6 |
35.2 |
|
|
ORa (95% CI) |
1.00 |
1.03(0.81,1.31) |
1.00(0.79,1.26) |
0.80 |
|
Monounsaturated Fatty Acids |
||||
|
No. of cases/controls |
341/509 |
342/506 |
371/476 |
|
|
Median intake (g/day) |
21.2 |
29.1 |
38.2 |
|
|
ORa (95% CI) |
1.00 |
1.07(0.84,1.35) |
0.99(0.78,1.26) |
0.70 |
|
Polyunsaturated Fatty Acids |
||||
|
No. of cases/controls |
357/493 |
343/505 |
372/475 |
|
|
Median intake (g/day) |
11.6 |
16.4 |
22.4 |
|
|
ORa (95% CI) |
1.00 |
1.03(0.81,1.30) |
0.98(0.77,1.23) |
0.47 |
|
Cholesterol |
||||
|
No. of cases/controls |
342/508 |
339/509 |
380/467 |
|
|
Median intake (mg/day) |
178.8 |
265.8 |
392.0 |
|
|
ORa (95% CI) |
1.00 |
0.84(0.65,1.07) |
1.00(0.79,1.28) |
0.88 |
|
Alcohol |
||||
|
No. of cases/controls |
382/467 |
309/539 |
344/503 |
|
|
Median intake (g/day) |
0 |
13.6 |
182.8 |
|
|
ORa (95% CI) |
1.00 |
0.88(0.67,1.17) |
1.17(0.85,1.61) |
0.38 |
|
|
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|
a Adjusted for total energy intake. Other potential confounders included age, sex, BMI, physical activity (METs/week), family history of CRC, polyps, diabetes, reported colon screening procedure, cigarette smoking, alcohol drinking, education attainment, household income, marital status, regular use of NSAID, regular use of multivitamin supplements, regular use of folate supplement, regular use of calcium supplement, reported HRT (females only), province of residence, and intakes of fruits, vegetables, and red meat. Variables were included in the final model based on a ≥ 10% alternation in the parameter coefficient of interest. b Two-sided p value for test of linear trend was calculated by using median values for each quintile of intake. e Q1 for quintile 1, Q3 for quintile 3, Q5 for quintile * Significant different from reference category, p ≤ 0.05 |
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|
Sun et al. Nutrition Journal 2012 11:18 doi:10.1186/1475-2891-11-18 |
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