Table 4

Odds ratios (ORs) and 95% confidence intervals (CIs) for rhinoconjunctivitis by quartiles of intake of specific fats in 1745 pregnant women, Kyushu Okinawa Maternal and Child Health Study, Japan

Quartile


Variable

1 (Lowest) (n = 436)

2 (n = 436)

3 (n = 436)

4 (Highest) (n = 437)

P for trend


Total fat

Intake, g/day*

47.2

54.7

60.4

69.7

Prevalence, %

23.9

25.2

25.7

28.8

Crude OR (95% CI)

1.00

1.08 (0.79-1.47)

1.10 (0.81-1.50)

1.29 (0.96-1.75)

0.10

Adjusted OR (95% CI)

1.00

1.09 (0.79-1.49)

1.11 (0.81-1.53)

1.31 (0.96-1.79)

0.09

Saturated fatty acids

Intake, g/day*

12.6

15.5

17.6

21.2

Prevalence, %

25.7

25.2

23.6

29.1

Crude OR (95% CI)

1.00

0.98 (0.72-1.32)

0.90 (0.66-1.22)

1.19 (0.88-1.60)

0.36

Adjusted OR (95% CI)

1.00

0.99 (0.72-1.35)

0.96 (0.70-1.32)

1.20 (0.88-1.63)

0.29

Monounsaturated fatty acids

Intake, g/day*

15.7

18.9

21.2

25.0

Prevalence, %

24.3

25.0

25.9

28.4

Crude OR (95% CI)

1.00

1.04 (0.76-1.41)

1.09 (0.80-1.48)

1.23 (0.91-1.67)

0.16

Adjusted OR (95% CI)

1.00

0.99 (0.72-1.36)

1.08 (0.79-1.48)

1.19 (0.87-1.63)

0.21

n-3 Polyunsaturated fatty acids

Intake, g/day*

1.7

2.1

2.4

2.9

Prevalence, %

25.5

25.2

24.8

28.2

Crude OR (95% CI)

1.00

0.99 (0.73-1.34)

0.96 (0.71-1.31)

1.15 (0.85-1.55)

0.42

Adjusted OR (95% CI)

1.00

0.92 (0.67-1.26)

0.90 (0.65-1.23)

1.07 (0.78-1.45)

0.72

α-Linolenic acid

Intake, g/day*

1.2

1.5

1.8

2.2

Prevalence, %

25.0

23.2

28.2

27.2

Crude OR (95% CI)

1.00

0.90 (0.66-1.23)

1.18 (0.87-1.59)

1.12 (0.83-1.52)

0.21

Adjusted OR (95% CI)

1.00

0.88 (0.64-1.21)

1.18 (0.86-1.60)

1.04 (0.76-1.42)

0.43

Eicosapentaenoic acid

Intake, g/day*

0.07

0.12

0.17

0.29

Prevalence, %

25.7

25.2

27.1

25.6

Crude OR (95% CI)

1.00

0.98 (0.72-1.32)

1.07 (0.79-1.45)

1.00 (0.74-1.35)

0.86

Adjusted OR (95% CI)

1.00

0.91 (0.67-1.25)

1.00 (0.73-1.37)

0.93 (0.68-1.28)

0.81

Docosahexaenoic acid

Intake, g/day*

0.14

0.22

0.30

0.46

Prevalence, %

25.2

25.2

29.4

23.8

Crude OR (95% CI)

1.00

1.00 (0.74-1.36)

1.23 (0.91-1.66)

0.93 (0.68-1.26)

0.98

Adjusted OR (95% CI)

1.00

0.93 (0.68-1.27)

1.13 (0.83-1.54)

0.88 (0.64-1.21)

0.73

n-6 Polyunsaturated fatty acids

Intake, g/day*

8.5

10.2

11.5

13.5

Prevalence, %

24.3

23.2

30.1

26.1

Crude OR (95% CI)

1.00

0.94 (0.69-1.28)

1.34 (0.99-1.81)

1.10 (0.81-1.49)

0.19

Adjusted OR (95% CI)

1.00

0.91 (0.66-1.26)

1.34 (0.98-1.83)

1.05 (0.77-1.45)

0.29

Linoleic acid

Intake, g/day*

8.3

10.0

11.3

13.1

Prevalence, %

24.3

23.6

29.1

26.5

Crude OR (95% CI)

1.00

0.96 (0.71-1.31)

1.28 (0.95-1.73)

1.13 (0.83-1.53)

0.19

Adjusted OR (95% CI)

1.00

0.94 (0.68-1.29)

1.27 (0.93-1.73)

1.08 (0.79-1.48)

0.30

Arachidonic acid

Intake, g/day*

0.09

0.12

0.14

0.18

Prevalence, %

25.0

24.1

28.4

26.1

Crude OR (95% CI)

1.00

0.95 (0.70-1.30)

1.19 (0.88-1.61)

1.06 (0.78-1.44)

0.42

Adjusted OR (95% CI)

1.00

0.90 (0.65-1.23)

1.20 (0.88-1.63)

1.05 (0.77-1.43)

0.39

n-3/n-6 Polyunsaturated fatty acid ratio

Intake*

0.17

0.19

0.21

0.25

Prevalence, %

24.8

26.8

27.8

24.3

Crude OR (95% CI)

1.00

1.11 (0.82-1.51)

1.17 (0.86-1.58)

0.97 (0.71-1.32)

0.95

Adjusted OR (95% CI)

1.00

1.07 (0.78-1.46)

1.07 (0.78-1.46)

0.92 (0.67-1.26)

0.61

Cholesterol

Intake, mg/day*

182.0

244.5

308.0

402.7

Prevalence, %

26.4

22.5

28.0

26.8

Crude OR (95% CI)

1.00

0.81 (0.59-1.10)

1.09 (0.81-1.46)

1.02 (0.76-1.38)

0.48

Adjusted OR (95% CI)

1.00

0.82 (0.60-1.13)

1.10 (0.81-1.49)

1.05 (0.77-1.42)

0.41


* Values for intake are medians for adjusted energy intake using the residual method for each quartile.

Prevalence of rhinoconjunctivitis based on the International Study of Asthma and Allergies in Childhood for each quartile.

Adjustment for age; gestation; region of residence; number of older siblings; number of children; smoking; secondhand smoke exposure at home and at work; family history of asthma, atopic eczema, and allergic rhinitis; household income; education; and body mass index.

Miyake et al. Nutrition Journal 2012 11:19   doi:10.1186/1475-2891-11-19

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