Table 1

Baseline characteristics of participants by MTHFR C677T or MTR A2756G polymorphism1

MTHFR C677T

MTR A2756G

All

CC

CT

TT

P

AA

AG/GG

P


N

445

114

221

110

365

80

Sex(Male), no.(%)

191(42.9)

51(44.7)

91(41.2)

49(44.5)

0.761

155(42.5)

36(45.0)

0.678

Age, yrs

57.0(9.8)

57.0(9.5)

56.4(9.6)

58.2(10.4)

0.284

57.0(9.8)

57.0(9.9)

0.971

BMI, kg/m2

25.7(3.5)

25.5(3.9)

25.8(3.3)

25.7(3.3)

0.758

25.8(3.5)

25.2(3.5)

0.137

SBP, mmHg

154.0(11.2)

154.0(11.5)

153.8(11.4)

154.5(10.5)

0.863

153.8(11.2)

155.1(11.2)

0.324

DBP, mmHg

93.0(8.3)

92.4(8.5)

93.4(7.8)

92.8(9.0)

0.530

93.3(8.0)

91.4(9.4)

0.052

FPG, mmol/L

5.5(1.3)

5.5(1.5)

5.4(1.2)

5.7(1.2)

0.312

5.5(1.3)

5.5(1.2)

0.865

TC, mmol/L

5.0(1.1)

5.0(1.4)

4.9(1.0)

5.1(1.0)

0.555

5.0(1.1)

4.9(1.1)

0.259

HDL-C, mmol/L

1.3(0.4)

1.3(0.4)

1.3(0.4)

1.3(0.4)

0.479

1.3(0.4)

1.3(0.3)

0.542

TG, mmol/L

1.7(1.2)

1.7(1.0)

1.8(1.2)

1.7(1.5)

0.970

1.8(1.3)

1.6(0.8)

0.252

Creatinine, μmol/L

69.5(17.5)

68.0(17.5)

69.2(17.3)

71.9(17.9)

0.233

69.2(17.9)

71.3(15.6)

0.334

Folate, nmol/L2

12.6(1.5)[12.3]

13.7(1.4)[13.4]

13.0(1.5)[12.6]

11.0(1.4)[10.8] *

< 0.001

12.8(1.5)[12.5]

11.9(1.5)[11.6]

0.107

Homocysteine, μmol/L2

13.2(1.6)[12.1]

11.2(1.4)[11.1]

12.0(1.4)[11.5]

18.8 (1.8)[17.5] *

< 0.001

13.1(1.6)[12.1]

13.3(1.6)[12.6]

0.794


BMI = body mass index, SBP = systolic blood pressure, DBP = diastolic blood pressure, FPG = fasting plasma glucose,

TC = total cholesterol, HDL-C = high-density lipoprotein cholesterol, TG = triglyceride;

1Means (SD); 2geometric mean (anti-log SD), median in brackets; * Significantly different from the CT or CC genotype, P < 0.001.

Qin et al. Nutrition Journal 2012 11:2   doi:10.1186/1475-2891-11-2

Open Data