Table 1 |
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|
Baseline characteristics of participants by MTHFR C677T or MTR A2756G polymorphism1 |
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|
MTHFR C677T |
MTR A2756G |
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|
All |
CC |
CT |
TT |
P |
AA |
AG/GG |
P |
|
|
|
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|
N |
445 |
114 |
221 |
110 |
365 |
80 |
||
|
Sex(Male), no.(%) |
191(42.9) |
51(44.7) |
91(41.2) |
49(44.5) |
0.761 |
155(42.5) |
36(45.0) |
0.678 |
|
Age, yrs |
57.0(9.8) |
57.0(9.5) |
56.4(9.6) |
58.2(10.4) |
0.284 |
57.0(9.8) |
57.0(9.9) |
0.971 |
|
BMI, kg/m2 |
25.7(3.5) |
25.5(3.9) |
25.8(3.3) |
25.7(3.3) |
0.758 |
25.8(3.5) |
25.2(3.5) |
0.137 |
|
SBP, mmHg |
154.0(11.2) |
154.0(11.5) |
153.8(11.4) |
154.5(10.5) |
0.863 |
153.8(11.2) |
155.1(11.2) |
0.324 |
|
DBP, mmHg |
93.0(8.3) |
92.4(8.5) |
93.4(7.8) |
92.8(9.0) |
0.530 |
93.3(8.0) |
91.4(9.4) |
0.052 |
|
FPG, mmol/L |
5.5(1.3) |
5.5(1.5) |
5.4(1.2) |
5.7(1.2) |
0.312 |
5.5(1.3) |
5.5(1.2) |
0.865 |
|
TC, mmol/L |
5.0(1.1) |
5.0(1.4) |
4.9(1.0) |
5.1(1.0) |
0.555 |
5.0(1.1) |
4.9(1.1) |
0.259 |
|
HDL-C, mmol/L |
1.3(0.4) |
1.3(0.4) |
1.3(0.4) |
1.3(0.4) |
0.479 |
1.3(0.4) |
1.3(0.3) |
0.542 |
|
TG, mmol/L |
1.7(1.2) |
1.7(1.0) |
1.8(1.2) |
1.7(1.5) |
0.970 |
1.8(1.3) |
1.6(0.8) |
0.252 |
|
Creatinine, μmol/L |
69.5(17.5) |
68.0(17.5) |
69.2(17.3) |
71.9(17.9) |
0.233 |
69.2(17.9) |
71.3(15.6) |
0.334 |
|
Folate, nmol/L2 |
12.6(1.5)[12.3] |
13.7(1.4)[13.4] |
13.0(1.5)[12.6] |
11.0(1.4)[10.8] * |
< 0.001 |
12.8(1.5)[12.5] |
11.9(1.5)[11.6] |
0.107 |
|
Homocysteine, μmol/L2 |
13.2(1.6)[12.1] |
11.2(1.4)[11.1] |
12.0(1.4)[11.5] |
18.8 (1.8)[17.5] * |
< 0.001 |
13.1(1.6)[12.1] |
13.3(1.6)[12.6] |
0.794 |
|
|
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|
BMI = body mass index, SBP = systolic blood pressure, DBP = diastolic blood pressure, FPG = fasting plasma glucose, TC = total cholesterol, HDL-C = high-density lipoprotein cholesterol, TG = triglyceride; 1Means (SD); 2geometric mean (anti-log SD), median in brackets; * Significantly different from the CT or CC genotype, P < 0.001. |
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|
Qin et al. Nutrition Journal 2012 11:2 doi:10.1186/1475-2891-11-2 |
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