Table 4 |
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| Volatile fatty acid (VFA) concentrations (μmol/g faeces) determined by tertbutyldimethylsilyl derivatisation and GC analysis for forty volunteers over the trial period during which they were consuming control, placebo or experimental bread products enriched with AXOS. (Mean values and standard deviations) | ||||||||||||||||
| baseline | control bread | pre- placebo treatment | placebo treatment | post- placebo washout | pre- AXOS treatment | AXOS treatment | post- AXOS washout | |||||||||
| Acetate | 45.6 | ±27.9 | 47.3 | ±21.8 | 51.1 | ±18.8 | 54.2 | ±26.4 | 48.0 | ±22.5 | 46.7 | ±22.3 | 55.1 | ±34.5 | 52.1 | ±19.6 |
| Propionate | 17.8 | ±13.7 | 16.5 | ±11.1 | 18.2 | ±10.1 | 19.5 | ±11.2 | 17.1 | ±10.9 | 16.1 | ±10.9c | 17.5 | ±10.4 | 18.8 | ±8.6b |
| Butyrate | 11.5 | ±7.9 | 13.6 | ±9.4 | 14.9 | ±10.1 | 14.6 | ±7.2a | 15.0 | ±10.1 | 12.8 | ±8.8 | 16.3 | ±12.3ab | 14.5 | ±7.9 |
| Total acetate, propionate and butyrate | 74.9 | ±44.7 | 77.4 | ±37.0 | 84.2 | ±33.3 | 87.8 | ±6.2 | 80.2 | ±38.3 | 75.6 | ±36.9 | 88.9 | ±52.4 | 85.4 | ±31.6 |
| Valerate | 1.2 | ±1.4 | 2.3 | ±2.3a | 2.4 | ±2.3a | 2.2 | ±1.8a | 2.0 | ±2.3 | 2.4 | ±1.5a | 2.3 | ±2.2a | 1.7 | ±2.0 |
| Iso-valerate | 1.3 | ±0.6 | 1.3 | ±1.0 | 1.5 | ±1.3 | 1.3 | ±1.1 | 1.7 | ±1.1 | 1.4 | ±0.7 | 1.1 | ±1.0 | 1.7 | ±2.0 |
| Caproate | 0.8 | ±0.8 | 0.7 | ±0.9 | 0.9 | ±1.3 | 1.0 | ±1.4 | 0.8 | ±0.8 | 0.8 | ±0.8 | 0.7 | ±0.8 | 1.1 | ±1.4 |
| Iso-butyrate | 1.7 | ±0.7 | 1.6 | ±1.2 | 1.9 | ±1.5 | 1.7 | ±1.3 | 1.8 | ±1.2 | 1.6 | ±0.9 | 1.3 | ±1.1 | 1.8 | ±1.3 |
| Total valerate, iso-valerate, caproate and iso-butyrate | 4.9 | ±2.5 | 5.8 | ±4.5 | 6.7 | ±5.0 | 6.2 | ±4.9a | 6.2 | ±3.7 | 6.1 | ±2.8 | 5.4 | ±4.2 | 6.3 | ±4.5 |
P-values of VFA changes. Wilcoxons signed rank test was used to determine statistical differences between levels of VFA, as this data did not follow a normal distribution.
a - different to baseline; b- different to pre-treatment; c- different to washout, (p < 0.05).
Walton et al. Nutrition Journal 2012 11:36 doi:10.1186/1475-2891-11-36
