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Table 3
Hazard ratios for overall and Gleason-specific prostate cancer by coffee consumption categories among 3527 men from the Collaborative cohort study who survived until 1stJanuary 1997
			Cups of coffee per day		*P-value for trend*
		0	1--2	≥3
All prostate cancer
	Total PC cases	81	67	38
	Hazard Ratio (95% CI)^a	reference	0.86 (0.62-1.20)	0.75 (0.50-1.11)	0.15
	Hazard Ratio (95% CI)^b	reference	0.84 (0.60-1.21)	0.74 (0.47-1.16)	0.23
Gleason < 7
	Total PC cases	17	17	07
	Hazard Ratio (95% CI)^a	reference	1.18 (0.59-2.35)	0.75 (0.30-1.87)	0.65
	Hazard Ratio (95% CI)^b	reference	1.04 (0.51-2.17)	0.54 (0.19-1.57)	0.48
Gleason = 7
	Total PC cases	12	14	12
	Hazard Ratio (95% CI)^a	reference	1.13 (0.51-2.50)	1.39 (0.60-3.22)	0.45
	Hazard Ratio (95% CI)^b	reference	1.23 (0.53-2.84)	1.79 (0.69-4.62)	0.17
Gleason 8-10
	Total PC cases	39	20	11
	Hazard Ratio (95% CI)^a	reference	0.52 (0.30-0.91)	0.45 (0.23-0.90)	0.01
	Hazard Ratio (95% CI)^b	reference	0.51 (0.28-0.92)	0.47 (0.22-1.01)	0.03
Unknown Gleason
	Total PC cases	13	16	08
	Hazard Ratio (95% CI)^a	reference	1.26 (0.59-2.69)	0.99 (0.40-2.49)	0.08
	Hazard Ratio (95% CI)^b	reference	1.17 (0.52-2.64)	0.88 (0.31-2.48)	0.89

Prostate cancer cases =186.

a = adjusted for age and social class, b = adjusted for age at screening, cholesterol, systolic blood pressure, BMI, alcohol intake, tea intake, smoking status, social class.

Shafique et al. Nutrition Journal 2012 11:42 doi:10.1186/1475-2891-11-42

Table 3