Table 1 |
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| Effects of Rimonabant with dietary intervention on physical and biochemical parameters over the study period (n = 20) (Mean ± SD) | ||
| Baseline | 6 Months | |
| Weight (Kg) | 112 ± 21 | 107 ± 21*** |
| Waist circumference (cm) | 124 ± 13 | 121 ± 13** |
| Fat mass (Kg) | 44 ± 12 | 42 ± 12 |
| HbA1c (%) | 8.0 ± 1.6 | 7.4 ± 1.7* |
| Total cholesterol (mmol/L) | 4.4 ± 1.0 | 4.4 ± 1.0 |
| LDL cholesterol (mmol/L) | 2.3 ± 0.8 | 2.4 ± 0.9 |
| HDL cholesterol (mmol/L) | 1.2 ± 0.2 | 1.3 ± 0.2** |
| Triglyceride (mmol/L) | 1.9 ± 1.1 | 1.7 ± 0.9 |
| Insulin dose (units / day) | 116 ± 59 | 102 ± 71* |
| Systolic blood pressure (mmHg) | 147 ± 21 | 142 ± 24 |
| Diastolic blood pressure (mmHg) | 85 ± 8 | 83 ± 11 |
*p < 0.05 in comparison to baseline.
**p < 0.01 in comparison to baseline.
***p < 0.001 in comparison to baseline.
Heppenstall et al. Nutrition Journal 2012 11:50 doi:10.1186/1475-2891-11-50