Table 3 |
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|
The predicted transcription factors binding to fatty acid-responsive element in the promoter of the gene involved in Hcy metabolism |
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|
Gene |
GeneID |
Transcript |
Factor |
Name(s) |
Chrom |
Start |
End |
|
|
|||||||
|
MTR |
4548 |
NM_000254 |
MA0066 |
PPARG |
chr1 |
236,956,831 |
236,956,850 |
|
MTR |
4548 |
NM_000254 |
MA0061 |
NF-kappaB |
chr1 |
236,958,560 |
236,958,569 |
|
HHCY |
191 |
NM_000687 |
MA0061 |
NF-kappaB |
chr20 |
32891257 |
32891266 |
|
HHCY |
191 |
NM_000687 |
M00242 |
PPARalpha:RXRalpha |
chr20 |
32891807 |
32891826 |
|
HHCY |
191 |
NM_000687 |
M00964 |
PXR, CAR, LXR, FXR |
chr20 |
32892802 |
32892813 |
|
HHCY |
191 |
NM_000687 |
T00720 |
RAR-gamma |
chr20 |
32891787 |
32891797 |
|
HHCY |
191 |
NM_000687 |
MA0074 |
RXRA::VDR |
chr20 |
32891381 |
32891395 |
|
CSE |
1491 |
NM_153742 |
M00774 |
NF-kappaB |
chr1 |
70876211 |
70876222 |
|
CSE |
1491 |
NM_153742 |
M00762 |
PPAR, HNF-4, COUP, |
chr1 |
70875793 |
70875805 |
|
CSE |
1491 |
NM_153742 |
M00518 |
PPARalpha:RXRalpha |
chr1 |
70876539 |
70876552 |
|
CSE |
1491 |
NM_153742 |
MA0065 |
PPARG::RXRA |
chr1 |
70876537 |
70876553 |
|
CSE |
1491 |
NM_153742 |
MA0074 |
RXRA::VDR |
chr1 |
70875356 |
70875369 |
|
CSE |
1491 |
NM_153742 |
T01331 |
RXR-alpha |
chr1 |
70876645 |
70876657 |
|
CBS |
875 |
NM_000071 |
MA0061 |
NF-kappaB |
chr21 |
44496816 |
44496825 |
|
CBS |
875 |
NM_000071 |
T00694 |
PPAR-alpha |
chr21 |
44496841 |
44496851 |
|
CBS |
875 |
NM_000071 |
MA0073 |
RREB1 |
chr21 |
44496183 |
44496202 |
|
CBS |
875 |
NM_000071 |
MA0074 |
RXRA::VDR |
chr21 |
44496362 |
44496376 |
|
CBS |
875 |
NM_000071 |
T01349 |
RXR-beta |
chr21 |
44496925 |
44496932 |
|
MAT1A |
4143 |
NM_000429 |
T05257 |
CAR2:RXR-alpha |
chr10 |
82051245 |
82051257 |
|
MAT1A |
4143 |
NM_000429 |
M00631 |
FXR/RXR-alpha |
chr10 |
82050669 |
82050682 |
|
MAT1A |
4143 |
NM_000429 |
MA0061 |
NF-kappaB |
chr10 |
82049620 |
82049629 |
|
MAT1A |
4143 |
NM_000429 |
MA0105 |
NFKB1 |
chr10 |
82049504 |
82049514 |
|
MAT1A |
4143 |
NM_000429 |
T02529 |
PPAR-gamma1 |
chr10 |
82051368 |
82051378 |
|
MAT1A |
4143 |
NM_000429 |
MA0074 |
RXRA::VDR |
chr10 |
82050026 |
82050040 |
|
MAT1A |
4143 |
NM_000429 |
T01331 |
RXR-alpha |
chr10 |
82050924 |
82050936 |
|
MTHFR |
4524 |
NM_005957 |
MA0066 |
PPARG |
chr1 |
11866220 |
11866239 |
|
MTHFR |
4524 |
NM_005957 |
T05313 |
FXR:RXR-alpha |
chr1 |
11867028 |
11867042 |
|
MTHFR |
4524 |
NM_005957 |
M00774 |
NF-kappaB |
chr1 |
11866612 |
11866623 |
|
MTHFR |
4524 |
NM_005957 |
M00518 |
PPARalpha:RXRalpha |
chr1 |
11867952 |
11867966 |
|
MTHFR |
4524 |
NM_005957 |
MA0065 |
PPARG::RXRA |
chr1 |
11867331 |
11867347 |
|
MTHFR |
4524 |
NM_005957 |
T02529 |
PPAR-gamma1 |
chr1 |
11867417 |
11867427 |
|
MTHFR |
4524 |
NM_005957 |
M00964 |
PXR, CAR, LXR, FXR |
chr1 |
11866787 |
11866798 |
|
|
|||||||
|
The predicted transcription factors (RXR-alpha) binding to n-3 PUFA-RE in the promoter of MTHFR, CSE, and MAT using web based software Mapper: http://genome.ufl.edu/mapper/ webcite. |
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|
Huang et al. Nutrition Journal 2012 11:6 doi:10.1186/1475-2891-11-6 |
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