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The effects of caffeinated and decaffeinated coffee on sex hormone-binding globulin and endogenous sex hormone levels: a randomized controlled trial

Nicole M Wedick1*, Christos S Mantzoros2,3, Eric L Ding1,4, Aoife M Brennan3, Bernard Rosner4,5, Eric B Rimm1,4,6, Frank B Hu1,4,6 and Rob M van Dam1,7

1 Department of Nutrition, Harvard School of Public Health, 665 Huntington Ave, Boston, MA, 02115, USA

2 Section of Endocrinology, Boston VA Healthcare System, Harvard Medical School, Boston, MA, USA

3 Division of Endocrinology, Diabetes & Metabolism, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA

4 Channing Laboratory, Department of Medicine, Brigham and Women’s Hospital, and Harvard Medical School, Boston, MA, USA

5 Department of Biostatistics, Harvard School of Public Health, Boston, MA, USA

6 Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA

7 Saw Swee Hock School of Public Health and Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, , Singapore

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Nutrition Journal 2012, 11:86 doi:10.1186/1475-2891-11-86

Published: 19 October 2012

Additional files

Additional file 1:

Table S1. Summary of the observational evidence for the relation between coffee and caffeine intake, SHBG and sex hormone levels. (DOC 47 kb)

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