Depiction of gut flora contribution to atopy. The neonatal immune system (Th0) is predisposed to develop Th2 responses, especially in the presence of atypical gut flora or the absence of lactobacilli and/or bifidobacteria. Therapies that stimulate Th1 responses may be able to restore balance and lead to immunologic tolerance rather than hypersensitivity.
Karpa et al. Nutrition Journal 2012 11:87 doi:10.1186/1475-2891-11-87