Table 5

Plasma concentrations of blood lipids, hs-CRP, and urea at baseline and changes after 4 wk and 8 wk of intervention with LPI and MPI
LPI MPI
Changes from baseline Changes from baseline Pa Pa
Baseline wk 4 wk 8 wk 4 wk 8 wk 4 wk 8
Total cholesterol (mmol/L) 6.54 ± 1.14 −0.12 ± 0.48 −0.05 ± 0.44 −0.22 ± 0.63 0.02 ± 0.49 0.36 0.52
LDL cholesterol (mmol/L) 4.38 ± 1.14 −0.26 ± 0.53** −0.08 ± 0.50 −0.32 ± 0.54** −0.06 ± 0.34 0.47 0.90
HDL cholesterol (mmol/L) 1.46 ± 0.45 0.04 ± 0.15 −0.05 ± 0.19 −0.03 ± 0.18 −0.02 ± 0.13 0.036 0.20
Triacylglyceroles (mmol/L) 1.77 ± 1.17 0.08 ± 0.59 0.19 ± 0.45* 0.17 ± 0.70 0.16 ± 0.77 0.59 0.77
LDL:HDL cholesterol ratio 3.32 ± 1.39 −0.29 ± 0.53** 0.02 ± 0.53 −0.20 ± 0.62 −0.05 ± 0.39 0.34 0.29
hs-CRPb, c (mg/L) 1.93 ± 2.12 −0.23 ± 1.29 −0.28 ± 1.38 −0.09 ± 1.17 −0.32 ± 1.41 0.63 0.89
Urea (mmol/L) 4.98 ± 1.30 0.59 ± 0.94*** 0.47 ± 1.10* 0.78 ± 1.19*** 0.44 ± 1.06* 0.36 0.86

Values are presented as means ± standard deviation, n = 33.

Abbreviation: LPI lupin protein isolate, MPI milk protein isolate, hs-CRP high-sensitivity C-reactive protein.

aP-value is for differences between treatments at wk 4 or at wk 8 determined by repeated measures ANOVA.

bData were not normally distributed and/or had heterogeneous variances, and thus were statistically analyzed using a linear mixed model.

c n = 23, hs-CRP values of some participants had to be excluded due to a temporary inflammatory status at time of measurement.

*, **, ***Significant differences comparing wk 4 and wk 8 with baseline determined by repeated measures ANOVA (*P ≤ 0.050, **P ≤ 0.010, ***P ≤ 0.001).

Bähr et al.

Bähr et al. Nutrition Journal 2013 12:107   doi:10.1186/1475-2891-12-107

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