Table 4

Changes in BIA and physical activity parameters at 6 months, by level of immunodeficiency at study entry (baseline)
Percentage change at 6 months from baseline, by CD4 count
Nutritional supplement Control
Parameter Baseline 6 months % change* Baseline 6 months % change p value
< 100 cells/mm3 N = 13 N = 9
Fat Free Mass (FFM; kg) 37.4 (34.2 – 43.2) 41.2 (35.6 – 51.7) 14.1 (1.6 – 19.2) 41.7 (39.1 – 47.1) 40.2 (35.7 – 42.9) 3.9 (−11.0 – 7.3) 0.811
Total Body Water (TBW; kg) 26.8 (23.5 – 31.4) 29.4 (24.9 – 36.8) 10.9 (2.5 – 21.1) 29.5 (26.5 – 36.3) 28.5 (25.2 – 30.9) 1.4 (−18.5 – 15.1) 0.806
Intracellular Water (ICW; kg) 14.3 (12.5 – 18.4) 16.6 (13.7 – 21.5) 13.6 (2.0 – 21.5) 16.8 (14.7 – 18.9) 15.8 (13.9 – 17.5) 1.6 (−18.0 – 15.7) 0.804
Extracellular Water (ECW; kg) 11.4 (10.6 – 14.1) 12.9 (11.5 – 15.4) 7.8 (3.0 – 19.9) 13.2 (11.3 – 17.2) 12.4 (11.6 – 14.2) 0.6 (−20.5 – 14.3) 0.805
Basal metabolic rate (BMR) 1264 (1205 – 1393) 1291 (1229 – 1520) 4.1 (2.4 – 9.2) 1348 (1285 – 1379) 1349 (1255 – 1403) 2.4 (−0.4 – 9.2) 0.179
Physical activity score 15.0 (14.0 – 20.0) 11.0 (10.5 – 12.5) −38.7 (−51.1 – -22.5) 14.0 (13.0 – 16.0) 11.5 (10.5 – 16.0) −8.9 (−25.9 – 9.8) 0.028
≥ 100 cells/mm3 N = 6 N = 10
Fat Free Mass (FFM; kg) 42.0 (25.5 – 42.8) 42.5 (36.3 – 44.2) 17.4 (5.0 – 29.8) 42.3 (37.8 – 50.0) 39.8 (35.5 – 52.4) −5.4 (−15.3 – -0.8) 0.025
Total Body Water (TBW; kg) 30.1 (19.1 – 30.4) 24.0 (12.0 – 32.7) 13.7 (7.0 – 20.4) 30.8 (25.0 – 36.5) 27.3 (24.2 – 38.6) −8.2 (−18.7 – 0.4) 0.143
Intracellular Water (ICW; kg) 16.0 (9.6 – 16.7) 15.9 (13.2 – 16.8) 16.0 (4.8 – 27.3) 18.6 (15.0 – 21.3) 16.8 (12.6 – 22.9) −7.9 (−18.3 – -2.2) 0.016
Extracellular Water (ECW; kg) 13.4 (9.5 – 14.4) 14.6 (10.8 – 15.9) 10.7 (9.4 – 12. 0) 12.0 (10.7 – 15.8) 11.6 (10.5 – 15.6) −3.2 (−19.9 – 0.9) 0.015
Basal metabolic rate (BMR) 1292 (1092 – 1345) 1418 (1226 – 1441) 8.0 (5.1 – 10.9) 1379 (1205 – 1471) 1365 (1190 – 1512) −0.8 (−1.6 – 1.2) 0.040
Physical activity score 19.5 (16.0 – 28.0) 13.0 (12.0 – 16.0) −36.8 (−53.6 – 33.3) 13.5 (12.0 – 17.0) 11.0 (10.0 – 18.0) −20.0 (−23.1 – 10.0) 0.630

*Median (IQR) of the differences (% change) between baseline and 6 months. The percentage change was compared between the two arms, nutritional supplement and Control arm.

Evans et al.

Evans et al. Nutrition Journal 2013 12:111   doi:10.1186/1475-2891-12-111

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