Table 4

Calcium-fiber interplay in the risk of colorectal cancer (CRC), colon cancer (CC) and rectal cancer (RC)
Fiber Calcium <1000 mg/d 1000-2000 mg/d >2000 mg/d
<6 g/d 1 (ref.) CRC: 0.55 (0.38-0.78) CRC: 0.39 (0.22-0.71)
CC: 0.47 (0.29-0.74) CC: 0.28 (0.13-0.62)
RC: 0.65 (0.41-1.01) RC: 0.54 (0.26-1.12)
6-8 g/d CRC: 0.58 (0.34-0.99) CRC: 0.42 (0.24-0.73) CRC: 0.30 (0.15-0.61)
CC: 0.60 (0.31-1.19) CC: 0.36 (0.18-0.74) CC: 0.22 (0.09-0.55)
RC: 0.60 (0.31-1.17) RC: 0.50 (0.25-1.02) RC: 0.42 (0.17-1.03)
>8 g/d CRC: 0.44 (0.20-0.98) CRC: 0.32 (0.14-0.71) CRC: 0.23 (0.09-0.56)
CC: 0.47 (0.17-1.30) CC: 0.28 (0.10-0.78) CC: 0.17 (0.05-0.54)
RC: 0.47 (0.17-1.30) RC: 0.39 (0.14-1.07) RC: 0.32 (0.10-1.02)

Stratum specified odds ratios with 95% confidence intervals for multivariable logistic regression* which include interaction terms between the exposure (calcium intake) and effect modifier (fiber intake).

*- adjusted for age [years], gender, education, fish consumption [servings/week], fruit, raw and cooked vegetable consumption [servings/day], fiber [g/day], vitamin C [mg/day], dietary iron [<=14,03 mg/day; >14,03 mg/day], alcohol consumption [g/week], adult lifetime recreational physical activity [METs-h/week], BMI [kg/m2], smoking [current, ex-smokers, non-smokers], taking mineral supplements [yes/no].

Galas et al.

Galas et al. Nutrition Journal 2013 12:134   doi:10.1186/1475-2891-12-134

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