Table 3

Dietary intake (24-hr recall) and basic biochemistry of the participants (normal & deficient)
All (n = 51) Normal (n = 22) Deficient (n = 29) p value
Age (years) 27.6(26,30) 29.0(27 – 31.0) 30.6 (28.5-32) ns
Male/female 14/37 4/18 10/19
Energy intake (calorie)/d 2240 (2080,2280) 2390 (2220,2480) 2200 (2080,2270) ns
Protein intake (g)/d 62 (52,80) 58 (50,82) 64 (55,80) ns
Fat (g/d) 45 (38,50) 44 (35,50) 43 (37,55) ns
Vitamin B-12 intake (μ g/day) 1.20 1.65 0.65 <0.02
(0.75,1.50) (1.4,1.85) (0.50,0.90)
Folate intake (μ g/day) 355 (320,400) 350.6 (310.4,415.4) 355.6 (318.2,425.4) ns
Hemoglobin (g/L) 127 (117,136) 124 (114,130) 128 (123,135) ns
Anemia% 14 14 14
Mean corpuscular volume (fL) 84.0 (81.0,90.5) 80.5 (75.0,85.0) 84.3 (82.2,90.4) ns
Plasma creatinine (mg/dL) 1.0 (0.9,1.1) 0.9 (0.8,1.1) 1.0 (0.9,1.1) ns
Plasma vitamin B-12* (pmol/L) 130 (98,217) 244 (187,306) 92.8 (71,117) <0.0001
Plasma holo-TC (pmol/L)* 19.6 (13.1-31.1) 27.7 (19.8,42.5) 14.4 (10.82,19.75) <0.0001
Plasma folate (ng/mL) 6.24 (4.2,14.90) 6.6 (4.0,15.2) 5.6 (4.6,12.8) ns
Plasma tHcy ** (μ mol/L) 21.1 (12.7,32.7) 11.9 (10.4,15.0) 31.9 (22.6,54.0) <0.001

Median(25th, 75th centile) ns-non significant.

p- difference between normal group & deficient group.

* Vitamin B-12 intake is directly associated with pl. vitamin B-12 and holo-TC concentrations(r = 0.52 & 0.27, p < 0.001 for both) adjusting for sex.

** vitamin B-12 intake is inversely associated with pl. tHcy concentrations(r = - 0.43, p < 0.001).

Naik et al.

Naik et al. Nutrition Journal 2013 12:136   doi:10.1186/1475-2891-12-136

Open Data