Table 2

Changed levels of coenzyme Q10, vitamin E, antioxidant enzymes activities, and inflammatory markers after supplementation
Placebo (n = 19) Q10-300 (n = 23) P values1
Coenzyme Q10 (μmol/L) −0.01 ± 0.09 (-0.03) 1.10 ± 0.54 (1.26) < 0.001b
Coenzyme Q10/TC (μmol/mmol) −0.01 ± 0.07 (-0.00) 0.25 ± 0.11 (0.25) < 0.001b
Vitamin E (μmol/L) −3.35 ± 4.51 (-3.08) −0.29 ± 4.03 (-0.83) 0.046b
Vitamin E/TC (μmol/mmol) −0.88 ± 1.45 (-0.55) 0.07 ± 1.08 (0.11) 0.032a
SOD (U/mg protein) 1.63 ± 21.54 (3.63) 15.90 ± 20.48 (12.91) 0.034a
CAT (U/mg protein) −1.42 ± 8.26 (-1.18) 6.17 ± 11.28 (3.18) 0.033b
GPx (U/mg protein) 0.91 ± 3.70 (-0.24) 4.62 ± 6.52 (2.15) 0.042b
CRP (mg/L) 0.39 ± 1.24 (0.00) −0.20 ± 0.73 (0.00) 0.343b
TNF-α (pg/mL) 0.17 ± 0.77 (0.08) −0.30 ± 0.35 (-0.26) 0.036b
IL-6 (pg/mL) 0.08 ± 0.64 (-0.11) −0.52 ± 0.79 (-0.14) 0.040a
Adiponectin (μg/mL) 0.36 ± 2.89 (0.30) 0.19 ± 1.88 (-0.20) 0.71b

Data are mean ± SD (median).

1values are significantly different between the placebo and the Q10-300 groups.

adata were analyzed by the Student’s t-test.

bdata were analyzed by the Mann-Whitney rank sum test.

CAT, catalase; CRP, C-reactive protein; GPx, glutathione peroxidase; IL-6, interleukin-6; SOD, superoxide dismutase; TC, total cholesterol; TNF-α, tumor necrosis factor-α.

Lee et al.

Lee et al. Nutrition Journal 2013 12:142   doi:10.1186/1475-2891-12-142

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