Table 2

Details of all subjects enrolled
Variable Tocotrienols (n = 43) Placebo (n = 44) P value
Gender (female) 23 (53.5%) 30 (68.2%) 0.160
Age in years (range) 52 ± 9 (36-74) 49 ± 7 (38-68) 0.177
BMI (kg/m2) 27.2 ± 4.6 27.1 ± 4.6 0.873
   Normoweight (BMI < 25) 16 (37.2%) 14 (31.8%)
  Overweight (25 < BMI < 30) 16 (37.2%) 21 (47.7%)
    Obese (30 < BMI < 40) 11 (25.6%) 8 (18.2%)
 Morbidly Obese (40 < BMI < 50) 0 (0.0%) 1 (2.3%)
TC (mmol/L) 5.9 ± 0.6 5.6 ± 0.6 0.075
HDL (mmol/L) 1.44 ± 0.35 1.37 ± 0.30 0.611
LDL (mmol/L) 3.7 ± 0.6 3.6 ± 0.6 0.168
TG (mmol/L) 1.5 ± 0.7 1.6 ± 0.8 0.889
ALP (IU/L) 76 ± 21 72 ± 18 0.826
AST (IU/L) 36 ± 14 38 ± 13 0.381
ALT (IU/L) 35 ± 16 39 ± 22 0.611
GGT (IU/L) 33 ± 19 32 ± 19 0.712
hs-Crp (mg/L) 4.3 ± 7.1 4.0 ± 5.4 0.865
Apo B (g/L) 1.25 ± 0.20 1.25 ± 0.21 0.952
Lp(A) (mg/dL) 17 ± 14 16 ± 16 0.449
Serum creatinine (μmol/L) 86 ± 13 78 ± 11 0.008
Fasting glucose (mmol/L) 5.4 ± 0.8 6.1 ± 2.3 0.557
      IFG ≥ 7.0 mmol/L 2 (4.7%) 7 (15.9%)
Systolic (mmHg) 134 ± 18 131 ± 15 0.524
Diastolic (mmHg) 80 ± 9 80 ± 9 0.976
Tobacco, current users 5 (11.6%) 5 (11.4%)
Mild NAFLD (score 3) 34 (79.1%) 35 (79.5%)
Moderate NAFLD (score 4) 7 (16.3%) 8 (18.2%)
Severe NAFLD (score 5-6) 2 (4.7%) 1 (2.3%)

Baseline biochemical, anthropometric and clinical parameters of all patients enrolled in the study (n = 87). Data are expressed as mean value ± SD; P < 0.05 is considered significant.

Table 2Abbreviations: BMI  Body Mass Index, TC  Total Cholesterol, HDL High Density Lipoprotein, LDL Low Density Lipoprotein, TG Triglycerides, ALP Alkaline Phosphatase, AST aspartate transaminase, ALT alanine transaminase, GGT gamma-glutamyl transpeptidase, hs-CRP high-sensitivity C-reactive protein, ApoB apolipoprotein B, LP(A) lipoprotein A, IFG Impaired Fasting Glucose, NAFLD Nonalcoholic Fatty Liver Disease.

[Wilcoxon rank test; Numbers’ 09, GraphPad].

Conversion factor mmol/L to mg/dL for optimal normal values:

TC 5.2 mmol/L = 200 mg/dL;

HDL 1.55 mmol/L = 60 mg/dL;

LDL 2.6 mmol/L = 100 mg/dL;

TG 1.7 mmol/L = 151 mg/dL.

Magosso et al.

Magosso et al. Nutrition Journal 2013 12:166   doi:10.1186/1475-2891-12-166

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