Table 3

Genotypes and alleles frequencies of the C667T and A1298C ( MTHFR ) polymorphisms in NAFLD patients and control subjects and statistical parameters
Genotypes and alleles NAFLD N (35) % P* Control N (45)% P** χ2 P***
MTHFR C677T
CC 12 (34.29) 0.996 23 (51.11) 0.360 0.154 0.345
CT 17 (48.57) 20 (44.45)
TT 06 (17.14) 02 (4.44)
CT+TT 23 (63.71) 22 (36.30)
Allele 677C 21 (0.58) 33 (0.73)
Allele 677T 14 (0.41) 12 (0.26)
MTHFR A1298C
AA 20 (57.15) 0.106 26 (57.79) 0.707 1.727 0.473
AC 15 (42.85) 17 (37.77)
CC 0 02 (4.44)
AC+CC 15 (50.31) 19 (49.68)
Allele 1298A 24 (0.78) 35 (0.76)
Allele 1298C 4 (0.21) 10 (0.23)

P*= Hardy-Weinberg Equilibrium NAFLD; P*= Hardy-Weinberg Equilibrium Control; χ2 = chi-square; P*** = Exact Fisher.

de Carvalho et al.

de Carvalho et al. Nutrition Journal 2013 12:37   doi:10.1186/1475-2891-12-37

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