Table 6

Pregnancy outcomes and neonatal anthropometry, overall and by study group
Outcome Overall Placebo Vitamin D p2
(n = 147) (n = 74) (n = 73)
Location of delivery1
   Shimantik Maternity centre 124 (84.4) 62 (83.8) 62 (84.9) 1.00
   Home 13 (8.8) 7 (9.7) 6 (8.2)
   Other hospital or clinic 1 (0.7) 0 (0) 1 (1.4)
   Other 9 (6.1) 5 (6.8) 4 (5.5)
Mode of delivery
   Vaginal 59 (40.1) 30 (40.5) 29 (39.7) 1.00
   C-section 88 (59.7) 44 (59.7) 44 (60.3)
Vaginal delivery3
   Spontaneous 54 (91.5) 28 (93.3) 26 (89.7) 0.80
   Forceps 3 (5.1) 1 (3.3) 2 (6.9)
   Unknown 2 (3.4) 1 (3.3) 1 (3.5)
Indication for c-section4
   Urgent 76 (81.7) 41 (89.1) 35 (74.5) 0.17
   Elective 11 (11.8) 3 (6.5) 8 (17.0)
   Unknown 6 (6.5) 2 (4.4) 4 (8.5)
Maternal serious clinical adverse events5 4 (2.5) 2 (2.7) 2 (2.7) 1.00
Gestational age at birth, wks6 38.4 ± 2.1 38.5 ± 2.1 38.2 ± 2.1 0.31
Infant anthropometry
   Birth weight, g7 2795 ± 467 2788 ± 378 2802 ± 543 0.86
   Length at birth, cm8 48.1 ± 2.5 48.0 ± 2.0 48.2 ± 2.5 0.55
   Head circumference, cm9 33.0 ± 1.7 33.0 ± 1.5 32.9 ± 1.8 0.71
Total births registered10 147 (91.9) 74 (92.5) 73 (91.3) 0.77
   Live births11 145 (98.6) 73 (98.6) 72 (98.6) 0.99
   Stillbirths11 2 (1.4) 1 (1.4) 1 (1.4) 1.00
Neonatal clinical adverse events
   Neonatal serious non-fatal adverse events 13 (8.8) 7 (9.5) 6 (8.2) 0.81
   Neonatal deaths 4 (2.8) 3 (4.1) 1 (1.4) 0.62

1 n (%).

2 p-value for Student’s t-test for means and Fischer’s exact test for proportions, conducted for variables with cell counts <5.

3 n = 59, as mode of delivery was vaginal.

4 n = 88, as mode of delivery was c-section.

5 Maternal serious adverse events included gastroenteritis, preterm delivery with premature rupture of membranes, injury (15% flame burn), and pre-eclampsia.

6 Mean ± standard deviation (SD).

7 Birth weight was missing for 2 infants in the placebo group and 1 in the vitamin D group.

8 n = 137 (69 in placebo, 68 in the vitamin D group).

9 n = 132 (65 in placebo, 67 in vitamin D group).

10 Denominator for calculation of proportions was the total number of women enrolled (n = 160).

11 Denominator for calculation of proportions was the total number of births registered (n = 147).

Roth et al.

Roth et al. Nutrition Journal 2013 12:47   doi:10.1186/1475-2891-12-47

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