Table 3

Biopharmaceutics Classification System of medications [31]
High solubility Low solubility
High permeability Class I Class II
High solubility Low solubility
High permeability High permeability
Transporter effects minimal Efflux (flows out) transporter effects predominate
Examples: Atropine, Caffeine, Diazepam, Glucose, Levodopa, Prednisolone Examples: Digoxin, Ibuprofen, Warfarin
Low permeability Class III Class IV
High solubility Low solubility
Low permeability Low permeability
Absorptive transporter effects predominate Absorptive and efflux transporter effects could be important
Examples: Atenolol, Captopril, Cimetidine, Acyclovir, Penicillin, Amoxicillin, Erythromycin Examples: Amphotericin B, Chlothalidone, Neomycin

Cichero

Cichero Nutrition Journal 2013 12:54   doi:10.1186/1475-2891-12-54

Open Data