|Correlation of phenylalanine and tyrosine concentrations and phenylalanine: tyrosine concentration ratio between different types of samples|
|Real time||Delay 1 h||Delay 2 h|
|Correlation between serum and dried blood|
|Correlation between serum and microdialysate|
Phe = phenylalanine; Tyr = tyrosine; [Phe]/[Tyr] = phenylalanine: tyrosine concentration ratio.
The correlation analysis of phenylalanine and tyrosine concentrations and of the phenylalanine: tyrosine concentration ratio ([Phe]/[Tyr]) between microdialysis fluid and serum was performed with samples taken simultaneously (“Real time”) and with microdialysate samples taken one hour (“Delay 1 h”) and two hours (“Delay 2 h”) after blood sampling. To assess the above-mentioned correlations Pearson’s correlation coefficients (r) were calculated for each patient, then transformed to Fisher-Z values (Fisher r-to-Z transformation) and averaged. Resulting mean Fisher-Z values were retransformed to r values (reversed Fisher transformation).
Grünert et al.
Grünert et al. Nutrition Journal 2013 12:60 doi:10.1186/1475-2891-12-60