Isotopic enrichment over time and multicompartmental model used to derive apolipoprotein A-I (apoAI) intravascular kinetic. Mean isotopic enrichment over time of plasma apoA-I for the 26 men with MetS (symbols), model-predicted values (lines) and multicompartmental model used to determined kinetic parameters of apoA-I (insert). Compartments 1–4 reflect the kinetic of plasma leucine. Compartment 5 represents the intracellular pool of leucine (hepatic and other tissues) from which apoAI is synthesized and appears into the circulation (compartment 7) after a delay (compartment 6).
Richard et al. Nutrition Journal 2013 12:76 doi:10.1186/1475-2891-12-76