Table 3

Mean values of all variables by VDR genotype in subjects without MetSyn
Variables VDR 2228570 C > T (Fok I) p VDR 1544410 A > G (Bsm I) p
FF Ff ff BB Bb bb
n = 130 n = 91 n = 22 n = 109 n = 102 n = 32
WC (cm) 89 (±10) 95 (±16) 90 (±9) 0.086 93 (±14) 93 (±13) 86 (±11) 0.293
Triglycerides (mg/dl) 90 (±28) 117 (±54)‡ 134 (±80) 0.005 107 (±46) 113 (±58) 100 (±45) 0.696
BPS (mmHg) 122 (±17) 121 (±21) 124 (±14) 0.923 119 (±21) 125 (±16) 121 (±21) 0.194
BPD (mmHg) 75 (±10) 76 (±14) 79 (±10) 0.316 75 (±13) 77 (±11) 74 (±14) 0.556
Fasting glucose (mg/dl) 92 (±10) 92 (±11) 89 (±10) 0.607 92 (±11) 90 (±9) 93 (±8) 0.588
HDL cholesterol (mg/dl) 50 (±11) 45 (±12)‡ 42 (±11) 0.031 47 (±13) 47 (±11) 42 (±6) 0.253
Homa IR 1.6 (±1.4) 1.7 (±1.4) 1.0 (±0.4) 0.398 1.7 (±1.7) 1.6 (±0.9) 1.2 (±0.7) 0.749
Homa β 92 (±62) 103 (±80) 87 (±93) 0.711 96 (±81) 107 (±71) 70 (±46) 0.424
25(OH)D3 (ng/ml) 20 (±6) 22 (±6.4) 24.4 (±5) 0.062 20.8 (±6) 23 (±6.4) 18 (±7.2)† 0.023
iPTH (pg/dl) 41 (±24) 36 (±18) 38 (±11) 0.019 40 (±20) 37 (±20) 32 (±24) 0.361

Legend:WC, Waist circumference; BPS, Systolic blood pressure; BPD, Diastolic blood pressure; HOMA IR, Insulin resistance; HOMA β, Cell function; iPTH, Intact parathyroid hormone; 25(OH)D3, Vitamin D. Data are expressed as mean (Standard Deviation). P values were calculated using ANOVA followed by Bonferroni test and adjusted for age. † significant for the heterozygous genotype; ‡ significant for the normal dominant homozygous genotype.

Schuch et al.

Schuch et al. Nutrition Journal 2013 12:96   doi:10.1186/1475-2891-12-96

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