|
levels of liver parameters at baseline after Robusta oil treatment and during follow-up |
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| Parameter |
Normal limits |
Baseline |
Treatment |
Follow-up1 |
Follow-up 2 |
|
|
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| n = 15 |
n = 15 |
n = 14 |
n = 14 |
||
| Alanine aminotransferase |
< 45 IU/l |
0.38 [0.36,0.56] |
0.67 [0.58,1.27]** |
0.49 [0.39,0.72]* |
0.39 [0.35,0.53] |
| Aspartate aminotransferase |
< 50 IU/l |
0.32 [0.26,0.38] |
0.44 [0.26,0.56] |
0.32 [0.28,0.42] |
0.38 [0.28,0.41] |
| Alkaline phosphatase |
40 – 125 U/l |
0.45 [0.36,0.58] |
0.43 [0.35,0.54] |
0.42 [0.34,0.51]* |
0.49 [0.37,0.53] |
| Amylase |
35 – 130 U/l |
0.50 [0.45,0.61] |
0.48 [0.38,0.52] |
0.49 [0.46,0.58] |
0.47 [0.42,0.57] |
| Bilirubin |
< 17 umol/l |
0.47 [0.41,0.65] |
0.53 [0.35,0.65] |
0.65 [0.57,0.82]** |
0.53 [0.40,0.74] |
| γ-glutamyltranspeptidase |
< 40 U/l for women < 75 U/l for men |
0.29 [0.24,0.38] |
0.25 [0.20,0.45] |
0.31 [0.27,0.51] |
0.34 [0.25,0.46] |
| Lactate dehydrogenase |
230 – 485 IU/l |
0.60 [0.56,0.61] |
0.61 [0.49,0.65] |
0.60 [0.50,0.64] |
0.54 [0.52,0.65] |
|
All values are medians in units of times the upper limit of normal with the 25th and 75th percentile between brackets. Treatment values were obtained after 16 days of Robusta oil treatment. Follow-up 1 took place four weeks after termination of the intervention and Follow-up2 eight weeks after termination. * value differs significantly from baseline (p < 0.05) in the Wilcoxon signed-rank test. ** p < 0.01 | |||||
Boekschoten et al. Nutrition Journal 2004 3:7 doi:10.1186/1475-2891-3-7 |
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