Table 3 |
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Antioxidant parameters in healthy volunteers after single ingestion of native or dealcoholized red wine |
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RW |
DRW |
Controls |
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Parameter |
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TPP, mg CE/L |
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Baseline |
15.1 ± 2.0 |
15.9 ± 2.0 |
13.9 ± 2.8 |
|
90 min |
17.7 ± 1.8*a |
18.3 ± 2.5* b |
14.3 ± 3.5a,b |
|
360 min |
15.5 ± 1.8* |
16.6 ± 2.0* |
14.3 ± 2.7* |
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TEAC, mmol/L |
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Baseline |
1.22 ± 0.08 |
1.25 ± 0.08 |
1.23 ± 0.05 |
|
90 min |
1.25 ± 0.07 |
1.28 ± 0.08 |
1.26 ± 0.05 |
|
360 min |
1.23 ± 0.08 |
1.24 ± 0.07 |
1.24 ± 0.04 |
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Vitamin C, mg/dL |
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Baseline |
1.33 ± 0.26 |
1.15 ± 0.18 |
1.14 ± 0.30 |
|
90 min |
1.27 ± 0.21 |
1.18 ± 0.18 |
1.17 ± 0.35 |
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360 min |
1.11 ± 0.22* |
1.35 ± 0.32* |
1.14 ± 0.26 |
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Uric acid, mg/dL |
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Baseline |
4.6 ± 1.0 |
4.8 ± 1.2 |
4.6 ± 1.1 |
|
90 min |
5.3 ± 1.0* |
4.9 ± 1.1 |
4.9 ± 1.2 |
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360 min |
4.5 ± 0.9 |
4.5 ± 1.0 |
4.4 ± 1.1 |
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Albumin, g/dL |
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Baseline |
4.1 ± 0.4 |
4.4 ± 0.4 |
4.1 ± 0.4 |
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90 min |
4.4 ± 0.4 |
4.4 ± 0.5 |
4.3 ± 0.3* |
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360 min |
4.4 ± 0.4 |
4.4 ± 0.5 |
4.4 ± 0.5 |
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Bilirubin, mg/dL |
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Baseline |
0.73 ± 0.44 |
0.69 ± 0.27 |
0.54 ± 0.23 |
|
90 min |
0.71 ± 0.37 |
0.68 ± 0.22 |
0.61 ± 0.27* |
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360 min |
0.52 ± 0.29* |
0.53 ± 0.26* |
0.50 ± 0.22 |
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TM0, arbitrary units |
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Baseline |
1,86 ± 0,48 |
1,98 ± 0,33 |
2,19 ± 0,67 |
|
90 min |
2,03 ± 0,43 |
2,36 ± 0,23 |
2,43 ± 0,43 |
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360 min |
2,61 ± 0,43* |
2,67 ± 0,24* |
2,33 ± 0,44 |
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TM300, arbitrary units |
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Baseline |
1,69 ± 0,92 |
1,43 ± 0,78 |
1,15 ± 1,07 |
|
90 min |
1,39 ± 0,65 |
1,05 ± 0,87 |
0,78 ± 1,23 |
|
360 min |
1,22 ± 0,67c |
0,21 ± 0,45*c,d |
1,21 ± 0,52d |
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Amounts of study drinks ingested were 200 mL red wine (RW), 175 mL dealcoholized red wine (DRW) or 200 mL water (Controls) TPP: total phenolic content in plasma; CE: catechin equivalents; TEAC: trolox equivalent antioxidant capacity; TM0: Tail Moment in untreated cells (endogenous DNA strand breaks); TM300: Tail Moment in cells treated with 300 μM H2O2 for 20 min (exogenous DNA strand breaks) Values are means ± SD, n = 9 for all experiments except for control group at 90 min, n = 7 for all parameters; DRW, n = 8 for TM0, TM300, and control group at 360 min, n = 6 for TM0, TM300 *Values different from baseline, P < 0.05 by Wilcoxon signed rank test a-dValues marked with identical letters differ between groups, P < 0.05 by Mann-Whitney U-test |
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Arendt et al. Nutrition Journal 2005 4:33 doi:10.1186/1475-2891-4-33 |
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