Table 3

Antioxidant parameters in healthy volunteers after single ingestion of native or dealcoholized red wine

RW

DRW

Controls


Parameter

TPP, mg CE/L

Baseline

15.1 ± 2.0

15.9 ± 2.0

13.9 ± 2.8

90 min

17.7 ± 1.8*a

18.3 ± 2.5* b

14.3 ± 3.5a,b

360 min

15.5 ± 1.8*

16.6 ± 2.0*

14.3 ± 2.7*

TEAC, mmol/L

Baseline

1.22 ± 0.08

1.25 ± 0.08

1.23 ± 0.05

90 min

1.25 ± 0.07

1.28 ± 0.08

1.26 ± 0.05

360 min

1.23 ± 0.08

1.24 ± 0.07

1.24 ± 0.04

Vitamin C, mg/dL

Baseline

1.33 ± 0.26

1.15 ± 0.18

1.14 ± 0.30

90 min

1.27 ± 0.21

1.18 ± 0.18

1.17 ± 0.35

360 min

1.11 ± 0.22*

1.35 ± 0.32*

1.14 ± 0.26

Uric acid, mg/dL

Baseline

4.6 ± 1.0

4.8 ± 1.2

4.6 ± 1.1

90 min

5.3 ± 1.0*

4.9 ± 1.1

4.9 ± 1.2

360 min

4.5 ± 0.9

4.5 ± 1.0

4.4 ± 1.1

Albumin, g/dL

Baseline

4.1 ± 0.4

4.4 ± 0.4

4.1 ± 0.4

90 min

4.4 ± 0.4

4.4 ± 0.5

4.3 ± 0.3*

360 min

4.4 ± 0.4

4.4 ± 0.5

4.4 ± 0.5

Bilirubin, mg/dL

Baseline

0.73 ± 0.44

0.69 ± 0.27

0.54 ± 0.23

90 min

0.71 ± 0.37

0.68 ± 0.22

0.61 ± 0.27*

360 min

0.52 ± 0.29*

0.53 ± 0.26*

0.50 ± 0.22

TM0, arbitrary units

Baseline

1,86 ± 0,48

1,98 ± 0,33

2,19 ± 0,67

90 min

2,03 ± 0,43

2,36 ± 0,23

2,43 ± 0,43

360 min

2,61 ± 0,43*

2,67 ± 0,24*

2,33 ± 0,44

TM300, arbitrary units

Baseline

1,69 ± 0,92

1,43 ± 0,78

1,15 ± 1,07

90 min

1,39 ± 0,65

1,05 ± 0,87

0,78 ± 1,23

360 min

1,22 ± 0,67c

0,21 ± 0,45*c,d

1,21 ± 0,52d


Amounts of study drinks ingested were 200 mL red wine (RW), 175 mL dealcoholized red wine (DRW) or 200 mL water (Controls)

TPP: total phenolic content in plasma; CE: catechin equivalents; TEAC: trolox equivalent antioxidant capacity; TM0: Tail Moment in untreated cells (endogenous DNA strand breaks);

TM300: Tail Moment in cells treated with 300 μM H2O2 for 20 min (exogenous DNA strand breaks)

Values are means ± SD, n = 9 for all experiments except for control group at 90 min, n = 7 for all parameters; DRW, n = 8 for TM0, TM300, and control group at 360 min, n = 6 for TM0, TM300

*Values different from baseline, P < 0.05 by Wilcoxon signed rank test

a-dValues marked with identical letters differ between groups, P < 0.05 by Mann-Whitney U-test

Arendt et al. Nutrition Journal 2005 4:33   doi:10.1186/1475-2891-4-33

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