Delayed-type hypersensitivity response in two age groups. DTH responses were assessed using the CMI multitest at baseline and at 6 weeks. Because of significant interaction between age and treatment group (p < 0.05), the population was split around the median age of 56 y in younger (< 56 y) and older (> 56 y) subjects. Average age of the younger subjects was 48 ± 4 y, with a BMI of 24.5 ± 2.8, comprising 12 men and 52 women. The average age of the older subjects was 65 ± 6 y, with a BMI of 26.0 ± 2.3, comprising of 30 men and 36 women. Both age categories were evenly spread over the treatments with 15–19 subjects per treatment per age category. Data are reported as LSM of the mean increase in the number of positive responses (A) and increase of the cumulative diameter of the positive responses (B). Responses in the micronutrient groups (micronutrient (white) and micronutrient + colostrum group (hatched)) are significantly different from levels in non-vitamin group (control (black) and colostrum group (grey)) with * p < 0.05.
Wolvers et al. Nutrition Journal 2006 5:28 doi:10.1186/1475-2891-5-28