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Maternal vitamin D deficiency associated with neonatal hypocalcaemic convulsions

Laxmi Camadoo1 email, Rebecca Tibbott2 email and Fernando Isaza3 email

Senior Registrar in Paediatrics, Nambour hospital, Mapleton Road, Nambour, Queensland, 4560, Australia

ST1 in Paediatrics, Ealing Hospital, Uxbridge Rd, Southall, UB1 3EU, London, UK

Consultant Paediatrician, Northwick Park Hospital, Harrow, Middlesex, HA1 3UJ, UK

author email corresponding author email

Nutrition Journal 2007, 6:23doi:10.1186/1475-2891-6-23

Published: 19 September 2007

Abstract

Maternal vitamin D insufficiency is not uncommon. Infants born to mothers who are deficient in vitamin D and or calcium, usually due to cultural modifications in their diets or clothing habits, and in addition are breastfed, are at risk of developing vitamin D deficiency and hypocalcaemia. We present a case of neonatal hypocalcaemic seizures secondary to vitamin D deficiency.

Rickets in children resulting from vitamin D deficiency is well documented. It is also becoming clear that there is a positive correlation between maternal vitamin D status during pregnancy and lactation and the development of rickets both in infancy and childhood. The correlation between maternal vitamin D, neonatal vitamin D and hypocalcaemia is not well documented.


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