Table 3 |
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|
Associations of BMI, percent body fat, central fat (trunk fat), peripheral fat, and lean mass with serum leptin concentrations |
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|
Leptin, ng/mL |
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|
Δ (95% C.I.) |
P-value |
Multiple R2 |
|
|
|
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|
BMI |
|||
|
Model 1 |
10.65 (8.16–13.19) |
< 0.0001 |
0.68 |
|
Model 2 |
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|
% Fat |
|||
|
Model 1 |
7.77 (6.56–8.98) |
< 0.0001 |
0.82 |
|
Model 2 |
7.20 (4.72–9.75) |
< 0.0001 |
0.82 |
|
Central fat |
|||
|
Model 1 |
11.93 (9.72–14.18) |
< 0.0001 |
0.77 |
|
Model 2 |
11.58 (5.87–17.61) |
0.0002 |
0.77 |
|
Peripheral fat |
|||
|
Model 1 |
10.55 (8.33–12.81) |
< 0.0001 |
0.72 |
|
Model 2 |
7.98 (2.13–14.16) |
0.01 |
0.73 |
|
Lean mass |
|||
|
Model 1 |
8.61 (3.76–13.68) |
0.001 |
0.31 |
|
Model 2 |
-0.85 (-4.81–3.25) |
0.68 |
0.68 |
|
|
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|
Δ - Percent change for serum leptin concentration for a one-unit change in each of the adiposity measures (i.e., percent change in leptin concentration per one-unit change in BMI, per 1% increase in total body fat, per 1 kg increase in central and peripheral fat and lean mass). Model 1: Adjusted for age, race, family history of breast cancer, parity and menarche < 12 years Model 2: Model 1 + BMI |
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|
Mahabir et al. Nutrition Journal 2007 6:3 doi:10.1186/1475-2891-6-3 |
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