Table 2

Liver Se-GSHPx activity and plasma GSH concentration of guinea pigs after 5 and 12 weeks on the experimental diets1

Diet Group

Liver Se-GSHPx (U/g protein)

Plasma GSH (uM/L)


Week 5

Week 12

Week 5

Week 12


Se-D/MC

15.02 ± 1.32a

14.36 ± 1.49a

7.55 ± 0.45a

4.23 ± 0.20a

(n = 8)

(n = 9)

(n = 8)

(n = 7)

Se-M/MC

33.97 ± 1.87b

30.84 ± 1.58b

8.44 ± 0.85a

3.86 ± 0.13a

(n = 11)

(n = 11)

(n = 8)

(n = 8)

Se-N/MC

46.78 ± 2.70c

35.52 ± 1.90b

7.38 ± 0.49a

4.12 ± 0.31a

(n = 11)

(n = 10)

(n = 8)

(n = 8)

Se-N/NC

57.04 ± 6.46c

43.12 ± 1.70c

7.52 ± 0.92a

4.33 ± 0.38a

(n = 11)

(n = 11)

(n = 8)

(n = 9)


1 Data from guinea pigs killed at both 24 and 48 hrs post AA dosing.

2 Values in a column without a common letter differ, P < 0.05. Values are means ± SEM.

3 n values are in parentheses.

Bertinato et al. Nutrition Journal 2007 6:7   doi:10.1186/1475-2891-6-7

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