Table 2

Nasal Symptom Scale scores and sneeze counts during late response phase

Comparison

Measure

Hours after

Nasal Allergen

Challenge

Treatment

Mean

N

SD

t

P (1-tailed)


Loratadine-

Placebo

Nasal

Symptoms

Score

2

Loratadine

5.1

18

3.5

-1.10

0.143

Placebo

5.9

18

3.1

4

Loratadine

4.1

18

3.4

-1.43

0.086

#

Placebo

5.1

18

3.1

6

Loratadine

3.2

18

2.8

-2.57

0.010

**

Placebo

4.4

18

3.6

8

Loratadine

3.1

18

2.6

-1.05

0.153

Placebo

3.8

18

3.4

AUC

Loratadine

15.5

18

10.7

-1.82

0.044

*

Placebo

19.3

18

12.6

Sneeze count

2

Loratadine

2.2

17

3.0

-1.25

0.114

Placebo

3.8

17

5.5

4

Loratadine

2.6

17

4.0

-0.52

0.306

Placebo

3.2

17

4.5

6

Loratadine

1.4

17

2.3

-2.22

0.021

*

Placebo

3.6

17

5.8

8

Loratadine

1.2

17

1.6

-1.89

0.038

*

Placebo

2.7

17

3.8

AUC

Loratadine

7.5

17

7.8

-1.79

0.047

*

Placebo

13.2

17

17.7

Placebo-CBP

Nasal

Symptoms

Score

2

Placebo

5.8

17

3.1

1.39

0.091

#

CBP

4.7

17

2.3

4

Placebo

4.9

17

3.1

1.71

0.053

#

CBP

3.6

17

2.3

6

Placebo

4.2

17

3.5

2.74

0.007

**

CBP

2.4

17

2.4

8

Placebo

3.5

17

3.3

0.90

0.190

CBP

2.8

17

2.6

AUC

Placebo

18.4

17

12.4

1.86

0.041

*

CBP

13.6

17

8.0

Sneeze count

2

Placebo

3.2

17

5.2

1.57

0.068

#

CBP

1.2

17

1.6

4

Placebo

2.7

17

4.4

1.72

0.052

#

CBP

1.2

17

1.9

6

Placebo

3.4

17

5.8

1.93

0.036

*

CBP

0.7

17

1.0

8

Placebo

2.3

17

3.7

0.90

0.191

CBP

1.5

17

2.3

AUC

Placebo

11.5

17

17.2

1.76

0.049

*

CBP

4.6

17

3.9

Loratadine-

CBP

Nasal

Symptoms

Score

2

Loratadine

4.8

17

3.4

0.14

0.447

CBP

4.7

17

2.3

4

Loratadine

3.9

17

3.4

0.28

0.393

CBP

3.6

17

2.3

6

Loratadine

3.1

17

2.8

1.43

0.086

#

CBP

2.4

17

2.4

8

Loratadine

2.9

17

2.6

0.20

0.421

CBP

2.8

17

2.6

AUC

Loratadine

14.7

17

10.5

0.51

0.308

CBP

13.6

17

8.0

Sneeze count

2

Loratadine

1.8

16

2.6

0.88

0.197

CBP

1.3

16

1.6

4

Loratadine

2.4

16

4.0

1.09

0.145

CBP

1.3

16

1.9

6

Loratadine

1.3

16

2.4

1.07

0.151

CBP

0.7

16

1.0

8

Loratadine

1.1

16

1.5

-0.55

0.295

CBP

1.4

16

2.3

AUC

Loratadine

6.6

16

7.1

1.18

0.128

CBP

4.7

16

4.1


# P < 0.10, * P < 0.05, ** P ≤ 0.01

Corren et al. Nutrition Journal 2008 7:20   doi:10.1186/1475-2891-7-20

Open Data