Table 1 |
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|
Baseline characteristics of the study subjects |
|||
| Variable |
Study group |
P value |
|
|
|
|||
| Hyal-Joint® (n = 11) |
Placebo (n = 9) |
||
| Men/women |
4/7 |
5/4 |
0.653 |
| Age, years, mean (SD) |
57.7 (10.1) |
54.6 (7.7) |
0.448 |
| Ethnicity |
0.361 |
||
| Black |
0 |
1 |
|
| Caucasian |
1 |
1 |
|
| Hispanic |
10 |
6 |
|
| Height, cm, mean (SD) |
164.7 (6.1) |
164.1 (10.8) |
0.889 |
| Weight, kg, mean (SD |
79.1 (26.3) |
80.9 (20.7) |
0.867 |
| Heart rate, beats/min, mean (SD) |
75.5 (12.3) |
75.7 (12.4) |
0.970 |
| Systolic BP, mm Hg, mean (SD) |
122.8 (16.4) |
135.6 (21.7) |
0.152 |
| Diastolic BP, mm Hg, mean (SD) |
77.8 (8.9) |
84.3 (10.4) |
0.148 |
| Rescue medication use (paracetamol 500 mg)* |
|||
| No. capsules (range) |
4 (0–19) |
9 (0–29) |
0.425 |
| Mean (SD) |
6.8 (7.3) |
9.9 (9.6) |
|
| WOMAC scores, mean (SD) |
|||
| Pain |
10.4 (3.0) |
10.1 (2.7) |
0.848 |
| Stiffness |
4.4 (1.0) |
4.4 (1.0) |
0.862 |
| Physical function |
37.7 (7.4) |
35.4 (11.5) |
0.597 |
| Aggregated total symptoms |
52.5 (10.8) |
50.0 (14.4) |
0.667 |
| SF-36v2 scores, mean (SD) |
|||
| Physical functioning |
30.8 (8.5) |
27.1 (8.5) |
0.342 |
| Role-physical |
35.3 (8.3) |
41.9 (7.8) |
0.084 |
| Bodily pain |
33.2 (4.8) |
36.9 (4.8) |
0.100 |
| General health |
44.1 (12.3) |
45.4 (10.3) |
0.814 |
| Vitality |
49.0 (11.3) |
50.4 (11.7) |
0.791 |
| Social functioning |
37.5 (12.0) |
43.5 (11.3) |
0.268 |
| Role-emotional |
36.1 (12.6) |
40.3 (12.9) |
0.467 |
| Mental health |
40.3 (19.7) |
47.5 (9.5) |
0.326 |
| Physical component summary (PCS-36) |
34.8 (6.3) |
34.6 (6.4) |
0.947 |
| Mental component summary (MCS-36) |
43.6 (17.5) |
50.6 (11.2) |
0.317 |
|
|
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|
*Between screening and randomization visits. |
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|
Kalman et al. Nutrition Journal 2008 7:3 doi:10.1186/1475-2891-7-3 |
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