Table 2 |
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|
Mean clinical biochemistry values of male rats administered PGX® for 90 days |
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|
Parameter (units) |
Control |
1.25% |
2.5% |
5.0% |
|
|
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|
Aspartate Aminotransferase (U/L) |
107 ± 32 |
82 ± 7 |
85 ± 15 |
92 ± 13 |
|
Alanine Aminotransferase (U/L) |
50 ± 16 |
43 ± 7 |
46 ± 9 |
48 ± 7 |
|
Sorbitol Dehydrogenase (U/L) |
8.4 ± 2.7 |
8.3 ± 3.0 |
8.2 ± 2.0 |
8.3 ± 2.0 |
|
Alkaline Phosphatase (U/L) |
107 ± 30 |
112 ± 32 |
96 ± 13 |
113 ± 25 |
|
Total Bilirubin (mg/dL) |
0.12 ± 0.01 |
0.12 ± 0.01 |
0.12 ± 0.02 |
0.13 ± 0.02 |
|
Blood Urea Nitrogen (mg/dL) |
17 ± 2 |
18 ± 2 |
16 ± 1 |
17 ± 2 |
|
Creatinine (mg/dL) |
0.31 ± 0.04 |
0.32 ± 0.03 |
0.32 ± 0.03 |
0.33 ± 0.03 |
|
Cholesterol (mg/dL) |
99 ± 19 |
102 ± 25 |
100 ± 15 |
92 ± 11 |
|
Triglycerides (mg/dL) |
36 ± 11 |
45 ± 19 |
44 ± 16 |
44 ± 10 |
|
Glucose (mg/dL) |
115 ± 12 |
113 ± 5 |
113 ± 8 |
109 ± 8 |
|
Total Protein (g/dL) |
6.2 ± 0.2 |
6.2 ± 0.2 |
6.2 ± 0.3 |
6.2 ± 0.2 |
|
Albumin (g/dL) |
3.1 ± 0.2 |
3.1 ± 0.1 |
3.2 ± 0.1 |
3.3 ± 0.1a |
|
Globulin (g/dL) |
3.1 ± 0.2 |
3.0 ± 0.2 |
3.0 ± 0.2 |
2.9 ± 0.2 |
|
Calcium (mg/dL) |
10.3 ± 0.3 |
10.3 ± 0.3 |
10.4 ± 0.3 |
10.7 ± 0.3 |
|
Inorganic Phosphorus (mg/dL) |
6.9 ± 0.4 |
7.0 ± 0.7 |
7.1 ± 0.6 |
7.5 ± 1.0 |
|
Sodium (mmol/L) |
144.2 ± 5.6 |
145.5 ± 4.8 |
145.0 ± 4.8 |
145.6 ± 6.2 |
|
Potassium (mmol/L) |
5.39 ± 0.28 |
5.39 ± 0.4 |
5.44 ± 0.23 |
5.34 ± 0.46 |
|
Chloride (mmol/L) |
102.4 ± 4.0 |
103.4 ± 3.3 |
102.9 ± 2.9 |
102.9 ± 4.1 |
|
|
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|
aStatistically different from control (P ≤ 0.05) by Dunn's test |
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|
Matulka et al. Nutrition Journal 2009 8:1 doi:10.1186/1475-2891-8-1 |
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