Table 2

Mean clinical biochemistry values of male rats administered PGX® for 90 days

Parameter (units)

Control

1.25%

2.5%

5.0%


Aspartate Aminotransferase (U/L)

107 ± 32

82 ± 7

85 ± 15

92 ± 13

Alanine Aminotransferase (U/L)

50 ± 16

43 ± 7

46 ± 9

48 ± 7

Sorbitol Dehydrogenase (U/L)

8.4 ± 2.7

8.3 ± 3.0

8.2 ± 2.0

8.3 ± 2.0

Alkaline Phosphatase (U/L)

107 ± 30

112 ± 32

96 ± 13

113 ± 25

Total Bilirubin (mg/dL)

0.12 ± 0.01

0.12 ± 0.01

0.12 ± 0.02

0.13 ± 0.02

Blood Urea Nitrogen (mg/dL)

17 ± 2

18 ± 2

16 ± 1

17 ± 2

Creatinine (mg/dL)

0.31 ± 0.04

0.32 ± 0.03

0.32 ± 0.03

0.33 ± 0.03

Cholesterol (mg/dL)

99 ± 19

102 ± 25

100 ± 15

92 ± 11

Triglycerides (mg/dL)

36 ± 11

45 ± 19

44 ± 16

44 ± 10

Glucose (mg/dL)

115 ± 12

113 ± 5

113 ± 8

109 ± 8

Total Protein (g/dL)

6.2 ± 0.2

6.2 ± 0.2

6.2 ± 0.3

6.2 ± 0.2

Albumin (g/dL)

3.1 ± 0.2

3.1 ± 0.1

3.2 ± 0.1

3.3 ± 0.1a

Globulin (g/dL)

3.1 ± 0.2

3.0 ± 0.2

3.0 ± 0.2

2.9 ± 0.2

Calcium (mg/dL)

10.3 ± 0.3

10.3 ± 0.3

10.4 ± 0.3

10.7 ± 0.3

Inorganic Phosphorus (mg/dL)

6.9 ± 0.4

7.0 ± 0.7

7.1 ± 0.6

7.5 ± 1.0

Sodium (mmol/L)

144.2 ± 5.6

145.5 ± 4.8

145.0 ± 4.8

145.6 ± 6.2

Potassium (mmol/L)

5.39 ± 0.28

5.39 ± 0.4

5.44 ± 0.23

5.34 ± 0.46

Chloride (mmol/L)

102.4 ± 4.0

103.4 ± 3.3

102.9 ± 2.9

102.9 ± 4.1


aStatistically different from control (P ≤ 0.05) by Dunn's test

Matulka et al. Nutrition Journal 2009 8:1   doi:10.1186/1475-2891-8-1

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