Table 3

Mean clinical biochemistry values of female rats administered PGX^® for 90 days

Parameter (units)

Control

1.25%

2.5%

5.0%

Aspartate Aminotransferase (U/L)

84 ± 13

86 ± 6

88 ± 10

101 ± 18^a

Alanine Aminotransferase (U/L)

32 ± 3

38 ± 4

40 ± 7

54 ± 14^a

Sorbitol Dehydrogenase (U/L)

10.0 ± 2.0

9.2 ± 1.7

10.3 ± 2.2

10.4 ± 2.0

Alkaline Phosphatase (U/L)

87 ± 31

97 ± 18

89 ± 25

103 ± 24

Total Bilirubin (mg/dL)

0.16 ± 0.03

0.16 ± 0.02

0.16 ± 0.02

0.18 ± 0.02

Blood Urea Nitrogen (mg/dL)

18 ± 2

17 ± 2

19 ± 1

18 ± 2

Creatinine (mg/dL)

0.41 ± 0.03

0.42 ± 0.04

0.44 ± 0.03

0.43 ± 0.04

Cholesterol (mg/dL)

98 ± 8

106 ± 11

102 ± 16

111 ± 13

Triglycerides (mg/dL)

25 ± 5

31 ± 8

29 ± 8

34 ± 8^a

Glucose (mg/dL)

115 ± 8

111 ± 7

115 ± 10

111 ± 7

Total Protein (g/dL)

6.5 ± 0.3

6.5 ± 0.2

6.5 ± 0.3

6.4 ± 0.3

Albumin (g/dL)

3.5 ± 0.2

3.5 ± 0.2

3.5 ± 0.2

3.5 ± 0.2

Globulin (g/dL)

3.0 ± 0.2

3.0 ± 0.2

3.1 ± 0.2

2.9 ± 0.2

Calcium (mg/dL)

10.7 ± 0.4

10.6 ± 0.3

10.5 ± 0.1

10.7 ± 0.4

Inorganic Phosphorus (mg/dL)

5.9 ± 0.5

5.5 ± 0.6

4.9 ± 0.4^b

5.4 ± 0.7

Sodium (mmol/L)

143.5 ± 5.8

141.0 ± 6.9

143.4 ± 5.6

136.6 ± 5.1^b

Potassium (mmol/L)

5.02. ± 0.28

4.88 ± 0.25

4.89 ± 0.25

4.71 ± 0.25^b

Chloride (mmol/L)

104.9 ± 4.0

102.3 ± 5.1

104.8 ± 3.4

100.4 ± 3.^b

^a Statistically different from control (P ≤ 0.05) by Dunn's test; ^b Statistically different from control (P≤ 0.05) by Dunnett test

Matulka et al. Nutrition Journal 2009 8:1   doi:10.1186/1475-2891-8-1