|
Changes in parameters before and after 2-week once daily oral administration of octanoic acid formula to cachectic patients with chronic respiratory disease. |
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| Before |
After |
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|
|
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| body mass index |
(kg/m2) |
16.0 ± 2.00 |
16.3 ± 2.00 |
p < 0.05 |
| appetite score |
40 ± 22 |
64 ± 27 |
p < 0.05 |
|
| acyl-ghrelin |
(fmol/ml) |
11.0 ± 11.1 |
14.8 ± 7.20 |
p < 0.05 |
| desacyl-ghrelin |
(fmol/ml) |
90.1 ± 52.4 |
90.9 ± 52.5 |
NS |
| total protein |
(g/dl) |
6.9 ± 0.6 |
7.3 ± 0.7 |
p < 0.05 |
| albumin |
(g/dl) |
3.8 ± 0.4 |
4.0 ± 0.4 |
p < 0.05 |
| total cholesterol |
(mg/dl) |
181 ± 40 |
184 ± 210 |
NS |
| fasting glucose |
(mg/dl) |
94 ± 9 |
91 ± 90 |
NS |
| prealbumin |
(mg/dl) |
15.8 ± 4.20 |
17.9 ± 3.90 |
p < 0.05 |
| transferrin |
(mg/dl) |
198 ± 41 |
231 ± 570 |
p < 0.05 |
| retinol binding protein |
(mg/dl) |
1.9 ± 0.4 |
2.3 ± 0.5 |
p < 0.05 |
| adrenalin |
(pg/ml) |
63 ± 40 |
60 ± 21 |
NS |
| noradrenalin |
(pg/ml) |
852 ± 320 |
724 ± 298 |
NS |
| dopamine |
(pg/ml) |
24 ± 10 |
18 ± 60 |
NS |
| GH |
(ng/ml) |
1.2 ± 1.0 |
1.3 ± 1.1 |
NS |
| IGF-1 |
(ng/ml) |
87 ± 36 |
98 ± 39 |
p < 0.05 |
|
Age: range 62–78 y; sex:8 women, 11 men; oral 400 ml octanoic acid formula administered once daily after breakfast in addition to food intake of 1,800 kcal | ||||
Ashitani et al. Nutrition Journal 2009 8:25 doi:10.1186/1475-2891-8-25 |
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