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Open Access Highly Accessed Review

Metabolic effects of low glycaemic index diets

Gabriela Radulian123*, Emilia Rusu123, Andreea Dragomir23 and Mihaela Posea2

Author Affiliations

1 "Carol Davila" University of Medicine, Bucharest, Romania

2 "N. Paulescu" National Institute of Diabetes, Nutrition and Metabolic Diseases, Bucharest, Romania

3 Foundation for Healthy Nutrition, Bucharest, Romania

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Nutrition Journal 2009, 8:5  doi:10.1186/1475-2891-8-5

Published: 29 January 2009


The persistence of an epidemic of obesity and type 2 diabetes suggests that new nutritional strategies are needed if the epidemic is to be overcome. A promising nutritional approach suggested by this thematic review is metabolic effect of low glycaemic-index diet.

The currently available scientific literature shows that low glycaemic-index diets acutely induce a number of favorable effects, such as a rapid weight loss, decrease of fasting glucose and insulin levels, reduction of circulating triglyceride levels and improvement of blood pressure.

The long-term effect of the combination of these changes is at present not known.

Based on associations between these metabolic parameters and risk of cardiovascular disease, further controlled studies on low-GI diet and metabolic disease are needed.