Table 1

Genes regulated by body weight/diet and alcohol consumption.

Category/Gene

Change


Water

Alcohol

CR

LF

HF

CR

LF

HF


Metabolism

Lep

-5.5

1

2.9

-3.1

1.8

2.6

Fbp2

-1.4

1

1.4a

-1.6

-1.8

1.5a

Gck

2.7

1

-2.9

2.6

2.3

-1.8

Ins1

3.9

1

-2.5

2.8

2.5

-2.7

Pltp

2.4

1

1.0a

2.5

1.9

1.2a

Apob

4.4

1

-1.7

3.6

1.6

-1.3a

Pck1

-1.5

1

1.4a

-1.6

-1.7

1.5

Ppp1r3a

-1.8

1

1.4a

-1.5

1.6

1.4

Aldh3a2

11

1

-5.8

9.5

3.1

-3.8

Lpin3

1.1a

1

3.4

1.0a

1.5

2.6

Lepr

-1.6

1

4

1.1a

1.5

2.4

Lpin2

8.3

1

-3.3

7.1

2.2

-2.3

Mlxipl

1.2a

1

-1.9

1.1a

1.8

-1.6

Apoa4

4.1

1

1.0a

4.2

1.7

1.1a

Mthfr

-2.5

1

1.1a

-2.4

-2.9

-1.2a

Akt2

2.1

1

1.1a

2

2

1.1a

Flot2

2.4

1

-1.3a

2.2

2.1

-1.2a

Nmu

-1.4a

1

3.3

1.2a

-1.6

2.7

Adrbk1

5.7

1

-1.3a

4

2.5

1.1a

Sst

2.9

1

-1.1a

2.5

2.5

1.1a

Adrb2

7.8

1

1.5

5.9

1.6

1.3a

Prl

11

1

-4

9

2.3

-2.4

Npy2r

3.2

1

1.2a

2.4

2

1.2a

Pro-inflammation

Cd68

1.0a

1

4.3

1.9

1.5

2.8

Ccr2

8.3

1

-1.4a

7.1

2.9

-1.4a

Anti-inflammation

Il10

4

1

1.5a

4.8

2.7

1.2a

Ptgds

3.7

1

1.1a

3.5

1.6

1.2a

Adrbk1

5.7

1

-1.3a

4

2.2

1.1a

Signal transducers, Growth factors

Raf1

1.0a

1

2.1

1.0a

2.1

2.3

Pde3b

-1.8

1

2.1

-1.8

-2.2

1.7

Pde3a

3.2

1

-1.1a

2.9

1.6

-1.2a

Gne

2.9

1

-1.1a

2.9

2.2

1.1a

Ptpn2

2.8

1

1.1a

1.8

1.5

-1.1a

Cblb

1.6a

1

-2.3

2.8a

3.4

-1.1a

Ptpn6

2.4

1

-1.6

1.8

1.8

-1.4

Ppp1cb

-1.8

1

1.8

-1.8

-1.4

1.6

Dusp9

19.2

1

-1.7

17

3.1

-1.2a

Itgb3

2.5

1

1.1a

2.4

2.4

1.2a

Prkx

5.9

1

2.9

4.3

2.3

1.8

Prkcz

4.3

1

-1.8

4.5

3.2

1.0a

Nras

5

1

-1.8

4

2

-1.6

Igfbp3

2.4

1

1.2a

2

3.1

1.0a

Miscellaneous

Eif4ebp2

4.5

1

-2.1

2.9

2.2

-1.6

Serpina6

3.5

1

-2.1

1.8

1.6

-1.7

Atp2a3

2.9

1

1.1a

3.3

2.5

1.2a

Stx1a

2.6

1

-1.6

1.9

1.5

-1.5a

Alms1

2.5

1

1.1a

2.8

2

1.2a

Sct

-2.8

1

1.0a

-2.6

-2

1.0a

Unc13a

3.6

1

-1.4a

2.7

1.5

-1.4a

Alb

3.3

1

-4

3.5

2.7

-3.4

Bbs1

1.0a

1

2.2

-1.2a

-1.7

1.8


a No significant change compared to Control. All others were significantly different compared to control mice, p < 0.05.

Paulson et al. Nutrition Journal 2010 9:14   doi:10.1186/1475-2891-9-14

Open Data