Table 4

Sustained Phase: Mean Change in Outcome Measures after Six Weeks of Treatment

Variable

Egg (n = 36)

Egg substitute (n = 36)

p-value


Endothelial Function

Flow Mediated Dilatation (%)

Baseline

5.6 ± 3.9

5.8 ± 3.9

0.78

6 Weeks

5.3 ± 4.1

6.9 ± 4.0

Change

-0.1 ± 1.5 (P = 0.80)

1.0 ± 1.2 (P < 0.01)

<0.01

Adjusted change†

-0.2 ± 1.3 (P = 0.35)

0.9 ± 1.4 (P < 0.01)

< 0.01

Stimulus adjusted response measure

Baseline

0.08 ± 0.10

0.06 ± 0.06

0.39

6 Weeks

0.08 ± 0.11

0.09 ± 0.09

Change

0.01 ± 0.05 (P = 0.54)

0.03 ± 0.06 (P < 0.01)

0.07

Lipid Panel

Total Cholesterol (mg/dL)

Baseline

244 ± 24

244 ± 24

1.00

6 Weeks

239 ± 27

227 ± 27

Change

-5 ± 21 (P = 0.10)

-18 ± 18 (P < 0.01)

< 0.01

Low Density Lipoprotein (mg/dL)

Baseline

168 ± 17

168 ± 17

6 Weeks

165 ± 24

154 ± 24

Change

-2 ± 19 (P = 0.30)

-14 ± 20 (P < 0.01)

0.01

High Density Lipoprotein (mg/dL)

Baseline

52 ± 15

52 ± 15

1.00

6 Weeks

51 ± 14

50 ± 13

Change

-1 ± 11 (P = 0.53)

-2 ± 10 (P = 0.15)

0.63

Triglycerides (mg/dL)

Baseline

132 ± 52

132 ± 52

1.00

6 Weeks

118 ± 47

116 ± 50

Change

-14 ± 37 (P = 0.02)

-18 ± 43 (P = 0.03)

0.83

Total Cholesterol to High Density Lipoprotein Ratio

Baseline

5.0 ± 1.3

5.0 ± 1.3

1.00

6 Weeks

5.0 ± 1.2

4.8 ± 1.3

Change

-0.06 ± 0.66 (P = 0.54)

-0.21 ± 0.82 (P = 0.11)

0.38

Body composition

Weight (kg)

Baseline

81 ± 19

81 ± 19

1.00

6 Weeks

82 ± 18

82 ± 18

Change

0.4 ± 2.3 (P = 0.33)

0.7 ± 2.4 (P = 0.08)

0.52

Body Mass Index (kg/m2)

Baseline

29.2 ± 4.5

29.2 ± 4.5

1.00

6 Weeks

29.3 ± 4.3

29.5 ± 4.5

Change

0.2 ± 0.8 (P = 0.13)

0.4 ± 0.9 (P = 0.04)

0.56


Values are mean ± SD; p-value obtained from ANOVA for repeated measurements except otherwise stated; p-values in parenthesis indicate within-group p-values; *p-value obtain from student ttest; Change = 6 Weeks - Baseline; † obtained from generalized linear models, controlling for age, blood pressure, LDL and BMI

Njike et al. Nutrition Journal 2010 9:28   doi:10.1186/1475-2891-9-28

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