Table 4 |
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|
Sustained Phase: Mean Change in Outcome Measures after Six Weeks of Treatment |
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|
Variable |
Egg (n = 36) |
Egg substitute (n = 36) |
p-value |
|
|
|||
|
Endothelial Function |
|||
|
Flow Mediated Dilatation (%) |
|||
|
Baseline |
5.6 ± 3.9 |
5.8 ± 3.9 |
0.78 |
|
6 Weeks |
5.3 ± 4.1 |
6.9 ± 4.0 |
|
|
Change |
-0.1 ± 1.5 (P = 0.80) |
1.0 ± 1.2 (P < 0.01) |
<0.01 |
|
Adjusted change† |
-0.2 ± 1.3 (P = 0.35) |
0.9 ± 1.4 (P < 0.01) |
< 0.01 |
|
Stimulus adjusted response measure |
|||
|
Baseline |
0.08 ± 0.10 |
0.06 ± 0.06 |
0.39 |
|
6 Weeks |
0.08 ± 0.11 |
0.09 ± 0.09 |
|
|
Change |
0.01 ± 0.05 (P = 0.54) |
0.03 ± 0.06 (P < 0.01) |
0.07 |
|
Lipid Panel |
|||
|
Total Cholesterol (mg/dL) |
|||
|
Baseline |
244 ± 24 |
244 ± 24 |
1.00 |
|
6 Weeks |
239 ± 27 |
227 ± 27 |
|
|
Change |
-5 ± 21 (P = 0.10) |
-18 ± 18 (P < 0.01) |
< 0.01 |
|
Low Density Lipoprotein (mg/dL) |
|||
|
Baseline |
168 ± 17 |
168 ± 17 |
|
|
6 Weeks |
165 ± 24 |
154 ± 24 |
|
|
Change |
-2 ± 19 (P = 0.30) |
-14 ± 20 (P < 0.01) |
0.01 |
|
High Density Lipoprotein (mg/dL) |
|||
|
Baseline |
52 ± 15 |
52 ± 15 |
1.00 |
|
6 Weeks |
51 ± 14 |
50 ± 13 |
|
|
Change |
-1 ± 11 (P = 0.53) |
-2 ± 10 (P = 0.15) |
0.63 |
|
Triglycerides (mg/dL) |
|||
|
Baseline |
132 ± 52 |
132 ± 52 |
1.00 |
|
6 Weeks |
118 ± 47 |
116 ± 50 |
|
|
Change |
-14 ± 37 (P = 0.02) |
-18 ± 43 (P = 0.03) |
0.83 |
|
Total Cholesterol to High Density Lipoprotein Ratio |
|||
|
Baseline |
5.0 ± 1.3 |
5.0 ± 1.3 |
1.00 |
|
6 Weeks |
5.0 ± 1.2 |
4.8 ± 1.3 |
|
|
Change |
-0.06 ± 0.66 (P = 0.54) |
-0.21 ± 0.82 (P = 0.11) |
0.38 |
|
Body composition |
|||
|
Weight (kg) |
|||
|
Baseline |
81 ± 19 |
81 ± 19 |
1.00 |
|
6 Weeks |
82 ± 18 |
82 ± 18 |
|
|
Change |
0.4 ± 2.3 (P = 0.33) |
0.7 ± 2.4 (P = 0.08) |
0.52 |
|
Body Mass Index (kg/m2) |
|||
|
Baseline |
29.2 ± 4.5 |
29.2 ± 4.5 |
1.00 |
|
6 Weeks |
29.3 ± 4.3 |
29.5 ± 4.5 |
|
|
Change |
0.2 ± 0.8 (P = 0.13) |
0.4 ± 0.9 (P = 0.04) |
0.56 |
|
|
|||
|
Values are mean ± SD; p-value obtained from ANOVA for repeated measurements except otherwise stated; p-values in parenthesis indicate within-group p-values; *p-value obtain from student ttest; Change = 6 Weeks - Baseline; † obtained from generalized linear models, controlling for age, blood pressure, LDL and BMI |
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|
Njike et al. Nutrition Journal 2010 9:28 doi:10.1186/1475-2891-9-28 |
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