Table 2

Effects of the 23-valent vaccine on Pneumococcal IgG antibodies

Antibody subtype

Day 0

Mean ± SD

Day 51

Mean ± SD

Day 72

Mean ± SD

Change

Days 0-51

Change

Days 0-72


Type 4

0.45 ± 0.64

2.21 ± 3.15

5.84 ± 7.35

0.023

0.042


Type 6B

0.95 ± 1.51

5.18 ± 6.64

5.19 ± 7.06

0.001

0.020


Type 9V

1.32 ± 4.10

6.07 ± 7.34

5.08 ± 5.25

0.129

0.095


Type 14

1.79 ± 2.56

9.91 ± 8.54

8.86 ± 8.59

0.000

0.006


Type 18C

0.72 ± 1.35

5.06 ± 5.80

4.93 ± 5.26

0.018

0.006


Type 19F

1.10 ± 2.94

7.02 ± 7.28

6.65 ± 7.26

0.011

0.015


Type 23F

1.08 ± 1.87

4.32 ± 4.62

4.55 ± 5.23

0.017

0.006


Increases in levels of antibody subtype as observed in the placebo group (n = 24) following inoculation with the 23-valent pneumococcal vaccine which took place on Day 30. Data are means (μg/dl) ± standard deviations on Days 0, 51 and 72. P-values for the changes between baseline and days 51 and 72 are in the right hand columns.

Udani et al. Nutrition Journal 2010 9:32   doi:10.1186/1475-2891-9-32

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