Table 1 |
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|
Changes on sputum smear AFB and radiograph after 2 and 6 months |
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|
Variables |
Groups |
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|
|
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|
Zinc |
Vitamin A |
Vitamin A + Zinc |
Placebo |
|
|
|
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|
Age (year), mean ± SD |
30.9 ± 11.8 |
33.1 ± 11.5 |
30.1 ± 12 |
31.4 ± 10.4 |
|
Gender (n,%): |
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|
Male |
51 (67.1) |
46 (63.9) |
42 (63.6) |
50 (58.1) |
|
Female |
25 (32.9) |
26 (36.1) |
24 (36.4) |
36 (41.9) |
|
Sputum smear grade (n,%): |
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|
+ 1 |
18 (23.7) |
22 (30.6) |
25 (37.9) |
24 (27.9) |
|
+ 2 |
24 (31.6) |
19 (26.4) |
18 (27.3) |
30 (34.9) |
|
+ 3 |
34 (44.7) |
31 (43) |
23 (34.8) |
32 (37.2) |
|
Sputum conversion time (wk),mean ±SD |
3.02 ± 2.2 |
2.1 ± 1.6 |
1.94 ± 1.4 |
2.5 ± 1.7 |
|
Duration to achieve WHO target(wk),mean † |
6.6 |
4.0 |
4.0 |
5.0 |
|
Number of cavity (n,%) |
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|
0 month* |
18 (25.7) |
35 (51.5) |
25 (38.5) |
36 (41.9) |
|
2 month* |
5 (7.5) |
17 (27) |
8 (14.8) |
13 (17.1) |
|
6 month |
5 (8.1) |
3 (5.3) |
2 (3.6) |
3 (4.2) |
|
Cavity surface area (cm2), median (IQR) |
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|
0 month |
10.2 (4.9-17.4) |
12.0 (6.2-22.1) |
12.9 (4.8-15.9) |
10.2 (4.9-21.6) |
|
2 month |
6.2 (2.5-21)‡ |
5.5 (2.5-13.7)‡ |
5.9 (2-16.2)‡ |
4 (3.1-10)‡ |
|
6 month |
0 (0 - 0)‡ |
0 (0 - 0)‡ |
0 (0- 0)‡ |
0 (0 - 0)‡ |
|
Total lesion area (cm2), median (IQR) |
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|
0 month |
120 (71-179.8) |
139 (44-216) |
143 (73-198) |
129 (62-209) |
|
2 month |
40.5 (12-100)‡ |
35 (0-80)‡ |
37 (9-94.5)‡ |
32.5 (4.5-77.5)‡ |
|
6 month |
0 (0-42.4)‡ |
0 (0-25.8)‡ |
0 (0-21)‡ |
0 (0-25.8)‡ |
|
|
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|
SD = standard deviation, IQR = interquartile range; *significant difference of proportion between groups (chi-squared, p < 0.05); significant changes from baseline p < 0.001‡; number of good quality sputum analyzed for zinc, vitamin A, zn + vitamin A and placebo groups were: 62, 57, 50, and 68 respectively (total 237). †WHO target: 85% subjects in a group converted into SS negative. |
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|
Pakasi et al. Nutrition Journal 2010 9:41 doi:10.1186/1475-2891-9-41 |
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