Table 1

Changes on sputum smear AFB and radiograph after 2 and 6 months

Variables

Groups


Zinc

Vitamin A

Vitamin A + Zinc

Placebo


Age (year), mean ± SD

30.9 ± 11.8

33.1 ± 11.5

30.1 ± 12

31.4 ± 10.4

Gender (n,%):

Male

51 (67.1)

46 (63.9)

42 (63.6)

50 (58.1)

Female

25 (32.9)

26 (36.1)

24 (36.4)

36 (41.9)

Sputum smear grade (n,%):

+ 1

18 (23.7)

22 (30.6)

25 (37.9)

24 (27.9)

+ 2

24 (31.6)

19 (26.4)

18 (27.3)

30 (34.9)

+ 3

34 (44.7)

31 (43)

23 (34.8)

32 (37.2)

Sputum conversion time (wk),mean ±SD

3.02 ± 2.2

2.1 ± 1.6

1.94 ± 1.4

2.5 ± 1.7

Duration to achieve WHO target(wk),mean †

6.6

4.0

4.0

5.0

Number of cavity (n,%)

0 month*

18 (25.7)

35 (51.5)

25 (38.5)

36 (41.9)

2 month*

5 (7.5)

17 (27)

8 (14.8)

13 (17.1)

6 month

5 (8.1)

3 (5.3)

2 (3.6)

3 (4.2)

Cavity surface area (cm2), median (IQR)

0 month

10.2 (4.9-17.4)

12.0 (6.2-22.1)

12.9 (4.8-15.9)

10.2 (4.9-21.6)

2 month

6.2 (2.5-21)‡

5.5 (2.5-13.7)‡

5.9 (2-16.2)‡

4 (3.1-10)‡

6 month

0 (0 - 0)‡

0 (0 - 0)‡

0 (0- 0)‡

0 (0 - 0)‡

Total lesion area (cm2), median (IQR)

0 month

120 (71-179.8)

139 (44-216)

143 (73-198)

129 (62-209)

2 month

40.5 (12-100)‡

35 (0-80)‡

37 (9-94.5)‡

32.5 (4.5-77.5)‡

6 month

0 (0-42.4)‡

0 (0-25.8)‡

0 (0-21)‡

0 (0-25.8)‡


SD = standard deviation, IQR = interquartile range; *significant difference of proportion between groups (chi-squared, p < 0.05); significant changes from baseline p < 0.001‡; number of good quality sputum analyzed for zinc, vitamin A, zn + vitamin A and placebo groups were: 62, 57, 50, and 68 respectively (total 237). †WHO target: 85% subjects in a group converted into SS negative.

Pakasi et al. Nutrition Journal 2010 9:41   doi:10.1186/1475-2891-9-41

Open Data